Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy
Background: CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen stroke risk scores are used to estimate thromboembolism risk. We aimed to investigate the association between unfavorable outcomes and stroke risk scores in patients who received e...
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MDPI AG
2022-09-01
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| Online Access: | https://www.mdpi.com/2077-0383/11/19/5599 |
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| author | Hyung Jun Kim Moo-Seok Park Joonsang Yoo Young Dae Kim Hyungjong Park Byung Moon Kim Oh Young Bang Hyeon Chang Kim Euna Han Dong Joon Kim JoonNyung Heo Jin Kyo Choi Kyung-Yul Lee Hye Sun Lee Dong Hoon Shin Hye-Yeon Choi Sung-Il Sohn Jeong-Ho Hong Jong Yun Lee Jang-Hyun Baek Gyu Sik Kim Woo-Keun Seo Jong-Won Chung Seo Hyun Kim Sang Won Han Joong Hyun Park Jinkwon Kim Yo Han Jung Han-Jin Cho Seong Hwan Ahn Sung Ik Lee Kwon-Duk Seo Yoonkyung Chang Hyo Suk Nam Tae-Jin Song |
| author_facet | Hyung Jun Kim Moo-Seok Park Joonsang Yoo Young Dae Kim Hyungjong Park Byung Moon Kim Oh Young Bang Hyeon Chang Kim Euna Han Dong Joon Kim JoonNyung Heo Jin Kyo Choi Kyung-Yul Lee Hye Sun Lee Dong Hoon Shin Hye-Yeon Choi Sung-Il Sohn Jeong-Ho Hong Jong Yun Lee Jang-Hyun Baek Gyu Sik Kim Woo-Keun Seo Jong-Won Chung Seo Hyun Kim Sang Won Han Joong Hyun Park Jinkwon Kim Yo Han Jung Han-Jin Cho Seong Hwan Ahn Sung Ik Lee Kwon-Duk Seo Yoonkyung Chang Hyo Suk Nam Tae-Jin Song |
| author_sort | Hyung Jun Kim |
| collection | DOAJ |
| description | Background: CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen stroke risk scores are used to estimate thromboembolism risk. We aimed to investigate the association between unfavorable outcomes and stroke risk scores in patients who received endovascular thrombectomy (EVT). Methods: This study was performed using data from a nationwide, multicenter registry to explore the selection criteria for patients who would benefit from reperfusion therapies. We calculated pre-admission CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen scores for each patient who received EVT and compared the relationship between these scores and 3-month modified Rankin Scale (mRS) records. Results: Among the 404 patients who received EVT, 213 (52.7%) patients had unfavorable outcomes (mRS 3–6). All scores were significantly higher in patients with unfavorable outcomes than in those with favorable outcomes. Multivariable logistic regression analysis indicated that CHADS<sub>2</sub> and the ATRIA score were positively correlated with unfavorable outcomes after adjusting for body mass index and variables with <i>p</i> < 0.1 in the univariable analysis (CHADS<sub>2</sub> score: odds ratio [OR], 1.484; 95% confidence interval [CI], 1.290–1.950; <i>p</i> = 0.005, ATRIA score, OR, 1.128; 95% CI, 1.041–1.223; <i>p</i> = 0.004). Conclusions: The CHADS<sub>2</sub> and ATRIA scores were positively correlated with unfavorable outcomes and could be used to predict unfavorable outcomes in patients who receive EVT. |
| first_indexed | 2024-03-09T21:35:23Z |
| format | Article |
| id | doaj.art-6ca8933ad8644cfe8a0f783cb35e5e6e |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T21:35:23Z |
| publishDate | 2022-09-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-6ca8933ad8644cfe8a0f783cb35e5e6e2023-11-23T20:45:40ZengMDPI AGJournal of Clinical Medicine2077-03832022-09-011119559910.3390/jcm11195599Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular ThrombectomyHyung Jun Kim0Moo-Seok Park1Joonsang Yoo2Young Dae Kim3Hyungjong Park4Byung Moon Kim5Oh Young Bang6Hyeon Chang Kim7Euna Han8Dong Joon Kim9JoonNyung Heo10Jin Kyo Choi11Kyung-Yul Lee12Hye Sun Lee13Dong Hoon Shin14Hye-Yeon Choi15Sung-Il Sohn16Jeong-Ho Hong17Jong Yun Lee18Jang-Hyun Baek19Gyu Sik Kim20Woo-Keun Seo21Jong-Won Chung22Seo Hyun Kim23Sang Won Han24Joong Hyun Park25Jinkwon Kim26Yo Han Jung27Han-Jin Cho28Seong Hwan Ahn29Sung Ik Lee30Kwon-Duk Seo31Yoonkyung Chang32Hyo Suk Nam33Tae-Jin Song34Department of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, KoreaDepartment of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, KoreaDepartment of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin 16995, KoreaDepartment of Neurology, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Keimyung University School of Medicine, Daegu 42601, KoreaDepartment of Radiology, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul 03722, KoreaCollege of Pharmacy, Yonsei Institute for Pharmaceutical Research, Yonsei University, Incheon 21983, KoreaDepartment of Radiology, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Seoul Medical Center, Seoul 02053, KoreaDepartment of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaBiostatistics Collaboration Unit, Department of Research Affairs, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Gachon University Gil Medical Center, Incheon 21565, KoreaDepartment of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, KoreaDepartment of Neurology, Keimyung University School of Medicine, Daegu 42601, KoreaDepartment of Neurology, Keimyung University School of Medicine, Daegu 42601, KoreaDepartment of Neurology, National Medical Center, Seoul 04564, KoreaDepartment of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang 10444, KoreaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, KoreaDepartment of Neurology, Yonsei University Wonju College of Medicine, Wonju 26426, KoreaDepartment of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, KoreaDepartment of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, KoreaDepartment of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin 16995, KoreaDepartment of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, KoreaDepartment of Neurology, Pusan National University School of Medicine, Busan 49241, KoreaDepartment of Neurology, Chosun University School of Medicine, Gwangju 61453, KoreaDepartment of Neurology, Sanbon Hospital, Wonkwang University School of Medicine, Gunpo 15865, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang 10444, KoreaDepartment of Neurology, Mokdong Hospital, College of Medicine, Ewha Woman’s University, Seoul 07985, KoreaDepartment of Neurology, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, KoreaBackground: CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen stroke risk scores are used to estimate thromboembolism risk. We aimed to investigate the association between unfavorable outcomes and stroke risk scores in patients who received endovascular thrombectomy (EVT). Methods: This study was performed using data from a nationwide, multicenter registry to explore the selection criteria for patients who would benefit from reperfusion therapies. We calculated pre-admission CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen scores for each patient who received EVT and compared the relationship between these scores and 3-month modified Rankin Scale (mRS) records. Results: Among the 404 patients who received EVT, 213 (52.7%) patients had unfavorable outcomes (mRS 3–6). All scores were significantly higher in patients with unfavorable outcomes than in those with favorable outcomes. Multivariable logistic regression analysis indicated that CHADS<sub>2</sub> and the ATRIA score were positively correlated with unfavorable outcomes after adjusting for body mass index and variables with <i>p</i> < 0.1 in the univariable analysis (CHADS<sub>2</sub> score: odds ratio [OR], 1.484; 95% confidence interval [CI], 1.290–1.950; <i>p</i> = 0.005, ATRIA score, OR, 1.128; 95% CI, 1.041–1.223; <i>p</i> = 0.004). Conclusions: The CHADS<sub>2</sub> and ATRIA scores were positively correlated with unfavorable outcomes and could be used to predict unfavorable outcomes in patients who receive EVT.https://www.mdpi.com/2077-0383/11/19/5599endovascular thrombectomyfunctional outcomeischemic strokestroke risk score |
| spellingShingle | Hyung Jun Kim Moo-Seok Park Joonsang Yoo Young Dae Kim Hyungjong Park Byung Moon Kim Oh Young Bang Hyeon Chang Kim Euna Han Dong Joon Kim JoonNyung Heo Jin Kyo Choi Kyung-Yul Lee Hye Sun Lee Dong Hoon Shin Hye-Yeon Choi Sung-Il Sohn Jeong-Ho Hong Jong Yun Lee Jang-Hyun Baek Gyu Sik Kim Woo-Keun Seo Jong-Won Chung Seo Hyun Kim Sang Won Han Joong Hyun Park Jinkwon Kim Yo Han Jung Han-Jin Cho Seong Hwan Ahn Sung Ik Lee Kwon-Duk Seo Yoonkyung Chang Hyo Suk Nam Tae-Jin Song Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy Journal of Clinical Medicine endovascular thrombectomy functional outcome ischemic stroke stroke risk score |
| title | Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy |
| title_full | Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy |
| title_fullStr | Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy |
| title_full_unstemmed | Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy |
| title_short | Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy |
| title_sort | association between chads sub 2 sub cha sub 2 sub ds sub 2 sub vasc atria and essen stroke risk scores and functional outcomes in acute ischemic stroke patients who received endovascular thrombectomy |
| topic | endovascular thrombectomy functional outcome ischemic stroke stroke risk score |
| url | https://www.mdpi.com/2077-0383/11/19/5599 |
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