Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection
COVID-19 infection poses an important clinical therapeutic problem, especially in patients with coexistent diseases such as type 2 diabetes. Potential pathogenetic links between COVID-19 and diabetes include inflammation, effects on glucose homeostasis, haemoglobin deoxygenation, altered immune stat...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/14/7605 |
_version_ | 1797526927003615232 |
---|---|
author | Weronika Bielka Agnieszka Przezak Andrzej Pawlik |
author_facet | Weronika Bielka Agnieszka Przezak Andrzej Pawlik |
author_sort | Weronika Bielka |
collection | DOAJ |
description | COVID-19 infection poses an important clinical therapeutic problem, especially in patients with coexistent diseases such as type 2 diabetes. Potential pathogenetic links between COVID-19 and diabetes include inflammation, effects on glucose homeostasis, haemoglobin deoxygenation, altered immune status and activation of the renin-angiotensin-aldosterone system (RAAS). Moreover, drugs often used in the clinical care of diabetes (dipeptidyl peptidase 4 inhibitors, glucagon-like peptide 1 receptor agonists, sodium-glucose cotransporter 2 inhibitors, metformin and insulin) may influence the course of SARS-CoV-2 infection, so it is very important to verify their effectiveness and safety. This review summarises the new advances in diabetes therapy and COVID-19 and provides clinical recommendations that are essential for medical doctors and for patients suffering from type 2 diabetes. |
first_indexed | 2024-03-10T09:36:18Z |
format | Article |
id | doaj.art-6ca93d7f18a44927a6105df7ebfc10eb |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-10T09:36:18Z |
publishDate | 2021-07-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-6ca93d7f18a44927a6105df7ebfc10eb2023-11-22T04:01:15ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-07-012214760510.3390/ijms22147605Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 InfectionWeronika Bielka0Agnieszka Przezak1Andrzej Pawlik2Department of Physiology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, PolandDepartment of Physiology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, PolandDepartment of Physiology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, PolandCOVID-19 infection poses an important clinical therapeutic problem, especially in patients with coexistent diseases such as type 2 diabetes. Potential pathogenetic links between COVID-19 and diabetes include inflammation, effects on glucose homeostasis, haemoglobin deoxygenation, altered immune status and activation of the renin-angiotensin-aldosterone system (RAAS). Moreover, drugs often used in the clinical care of diabetes (dipeptidyl peptidase 4 inhibitors, glucagon-like peptide 1 receptor agonists, sodium-glucose cotransporter 2 inhibitors, metformin and insulin) may influence the course of SARS-CoV-2 infection, so it is very important to verify their effectiveness and safety. This review summarises the new advances in diabetes therapy and COVID-19 and provides clinical recommendations that are essential for medical doctors and for patients suffering from type 2 diabetes.https://www.mdpi.com/1422-0067/22/14/7605COVID-19diabetestherapy |
spellingShingle | Weronika Bielka Agnieszka Przezak Andrzej Pawlik Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection International Journal of Molecular Sciences COVID-19 diabetes therapy |
title | Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection |
title_full | Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection |
title_fullStr | Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection |
title_full_unstemmed | Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection |
title_short | Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection |
title_sort | therapy of type 2 diabetes in patients with sars cov 2 infection |
topic | COVID-19 diabetes therapy |
url | https://www.mdpi.com/1422-0067/22/14/7605 |
work_keys_str_mv | AT weronikabielka therapyoftype2diabetesinpatientswithsarscov2infection AT agnieszkaprzezak therapyoftype2diabetesinpatientswithsarscov2infection AT andrzejpawlik therapyoftype2diabetesinpatientswithsarscov2infection |