Two New Xanthones from Calophyllum nodusum (Guttiferae)
The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separat...
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MDPI AG
2011-10-01
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Series: | Molecules |
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author | Gwendoline Cheng Lian Ee Rusea Go Nur Kartinee Kassim Siti Noor Kamilah Muhamad Khozirah Shaari Mawardi Rahmani Nadiah Mad Nasir Mohd Johadi Iskandar |
author_facet | Gwendoline Cheng Lian Ee Rusea Go Nur Kartinee Kassim Siti Noor Kamilah Muhamad Khozirah Shaari Mawardi Rahmani Nadiah Mad Nasir Mohd Johadi Iskandar |
author_sort | Gwendoline Cheng Lian Ee |
collection | DOAJ |
description | The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone (1a) and trapezifolixanthone A (2). Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data. |
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format | Article |
id | doaj.art-6caaf45818404ebdb3deca2569bc73a9 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-12-13T04:00:02Z |
publishDate | 2011-10-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-6caaf45818404ebdb3deca2569bc73a92022-12-22T00:00:30ZengMDPI AGMolecules1420-30492011-10-0116118973898010.3390/molecules16118973Two New Xanthones from Calophyllum nodusum (Guttiferae)Gwendoline Cheng Lian EeRusea GoNur Kartinee KassimSiti Noor Kamilah MuhamadKhozirah ShaariMawardi RahmaniNadiah Mad NasirMohd Johadi IskandarThe air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone (1a) and trapezifolixanthone A (2). Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data.http://www.mdpi.com/1420-3049/16/11/8973/Calophyllum nodusumnodusuxanthonetrapezifolixanthone Alupeolstigmasterol |
spellingShingle | Gwendoline Cheng Lian Ee Rusea Go Nur Kartinee Kassim Siti Noor Kamilah Muhamad Khozirah Shaari Mawardi Rahmani Nadiah Mad Nasir Mohd Johadi Iskandar Two New Xanthones from Calophyllum nodusum (Guttiferae) Molecules Calophyllum nodusum nodusuxanthone trapezifolixanthone A lupeol stigmasterol |
title | Two New Xanthones from Calophyllum nodusum (Guttiferae) |
title_full | Two New Xanthones from Calophyllum nodusum (Guttiferae) |
title_fullStr | Two New Xanthones from Calophyllum nodusum (Guttiferae) |
title_full_unstemmed | Two New Xanthones from Calophyllum nodusum (Guttiferae) |
title_short | Two New Xanthones from Calophyllum nodusum (Guttiferae) |
title_sort | two new xanthones from calophyllum nodusum guttiferae |
topic | Calophyllum nodusum nodusuxanthone trapezifolixanthone A lupeol stigmasterol |
url | http://www.mdpi.com/1420-3049/16/11/8973/ |
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