Recent Advances in Biotransformation of Saponins
Saponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants. Rare saponins, a special type of the saponins class, are able to enhance bidirectional im...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/24/13/2365 |
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| author | Yi He Zhuoyu Hu Aoran Li Zhenzhou Zhu Ning Yang Zixuan Ying Jingren He Chengtao Wang Sheng Yin Shuiyuan Cheng |
| author_facet | Yi He Zhuoyu Hu Aoran Li Zhenzhou Zhu Ning Yang Zixuan Ying Jingren He Chengtao Wang Sheng Yin Shuiyuan Cheng |
| author_sort | Yi He |
| collection | DOAJ |
| description | Saponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants. Rare saponins, a special type of the saponins class, are able to enhance bidirectional immune regulation and memory, and have anti-lipid oxidation, anticancer, and antifatigue capabilities, but they are infrequent in nature. Moreover, the in vivo absorption rate of saponins is exceedingly low, which restricts their functions. Under such circumstances, the biotransformation of these ingredients from normal saponins—which are not be easily adsorbed by human bodies—is preferred nowadays. This process has multiple advantages, including strong specificity, mild conditions, and fewer byproducts. In this paper, the biotransformation of natural saponins—such as ginsenoside, gypenoside, glycyrrhizin, saikosaponin, dioscin, timosaponin, astragaloside and ardipusilloside—through microorganisms (<i>Aspergillus</i> sp., lactic acid bacteria, bacilli, and intestinal microbes) will be reviewed and prospected. |
| first_indexed | 2024-12-13T00:06:03Z |
| format | Article |
| id | doaj.art-6caccf4cc3e9409b81671958506e9cdf |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T00:06:03Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6caccf4cc3e9409b81671958506e9cdf2022-12-22T00:06:14ZengMDPI AGMolecules1420-30492019-06-012413236510.3390/molecules24132365molecules24132365Recent Advances in Biotransformation of SaponinsYi He0Zhuoyu Hu1Aoran Li2Zhenzhou Zhu3Ning Yang4Zixuan Ying5Jingren He6Chengtao Wang7Sheng Yin8Shuiyuan Cheng9National R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaBeijing Engineering and Technology Research Center of Food Additives, Beijing Technology & Business University (BTBU), Beijing 100048, ChinaBeijing Engineering and Technology Research Center of Food Additives, Beijing Technology & Business University (BTBU), Beijing 100048, ChinaNational R&D Center for Se-rich Agricultural Products Processing, College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaSaponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants. Rare saponins, a special type of the saponins class, are able to enhance bidirectional immune regulation and memory, and have anti-lipid oxidation, anticancer, and antifatigue capabilities, but they are infrequent in nature. Moreover, the in vivo absorption rate of saponins is exceedingly low, which restricts their functions. Under such circumstances, the biotransformation of these ingredients from normal saponins—which are not be easily adsorbed by human bodies—is preferred nowadays. This process has multiple advantages, including strong specificity, mild conditions, and fewer byproducts. In this paper, the biotransformation of natural saponins—such as ginsenoside, gypenoside, glycyrrhizin, saikosaponin, dioscin, timosaponin, astragaloside and ardipusilloside—through microorganisms (<i>Aspergillus</i> sp., lactic acid bacteria, bacilli, and intestinal microbes) will be reviewed and prospected.https://www.mdpi.com/1420-3049/24/13/2365saponinsbiotransformationmicroorganismsbioavailability |
| spellingShingle | Yi He Zhuoyu Hu Aoran Li Zhenzhou Zhu Ning Yang Zixuan Ying Jingren He Chengtao Wang Sheng Yin Shuiyuan Cheng Recent Advances in Biotransformation of Saponins Molecules saponins biotransformation microorganisms bioavailability |
| title | Recent Advances in Biotransformation of Saponins |
| title_full | Recent Advances in Biotransformation of Saponins |
| title_fullStr | Recent Advances in Biotransformation of Saponins |
| title_full_unstemmed | Recent Advances in Biotransformation of Saponins |
| title_short | Recent Advances in Biotransformation of Saponins |
| title_sort | recent advances in biotransformation of saponins |
| topic | saponins biotransformation microorganisms bioavailability |
| url | https://www.mdpi.com/1420-3049/24/13/2365 |
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