Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis

Abstract Introduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders and its prognosis is still debated. Objective: We aimed to review long-term follow-up data in patients with CAE and to evaluate the prognosis of CAE patients with coronary slow flow phenomenon (CSF...

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Main Authors: Mehmet Kaplan, Özge Özcan Abacıoğlu, Fethi Yavuz, Gizem Ilgın Kaplan, Mustafa Topuz
Format: Article
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular 2021-06-01
Series:Brazilian Journal of Cardiovascular Surgery
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382021000300346&tlng=en
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author Mehmet Kaplan
Özge Özcan Abacıoğlu
Fethi Yavuz
Gizem Ilgın Kaplan
Mustafa Topuz
author_facet Mehmet Kaplan
Özge Özcan Abacıoğlu
Fethi Yavuz
Gizem Ilgın Kaplan
Mustafa Topuz
author_sort Mehmet Kaplan
collection DOAJ
description Abstract Introduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders and its prognosis is still debated. Objective: We aimed to review long-term follow-up data in patients with CAE and to evaluate the prognosis of CAE patients with coronary slow flow phenomenon (CSFP). Methods: This study had a prospective design and 143 patients with CAE were included. The angiographic and demographic characteristics were reviewed in detail. The patients were categorized, based on concomitant coronary artery stenosis detected by angiography, as CCAE group (n=87, ≥30% luminal stenosis) and ICAE group (n=56, <30% luminal stenosis) and also categorized by the coronary flow as CSFP group (n=51) and normal flow coronary ectasia - NCEA group (n=92). All patients were re-evaluated at 6-month intervals. Follow-up data, cardiovascular (CV) mortality, hospitalization and major adverse cardiac events (MACE) were collected. The level of statistical significance was set at 5%. Results: Patients were followed up for an average of 56.9±7.4 months. During the follow-up, statistically significant differences were found in hospitalization, CV mortality and MACE between the CCAE and ICAE groups (P=0.038, P=0.003, P=0.001, respectively). The CSFP and NCEA groups were also compared. There was a statistical difference with respect to hospitalization between the CFSP and NCEA groups (P=0.001), but no difference was observed in terms of MACE and CV mortality (P=0.793 and P=0.279). Conclusion: CSFP accompanying CAE may be a predictor of hospitalization. Significant atherosclerotic plaques coexisting with CAE may be predictive for MACE.
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spelling doaj.art-6cb019bb1f494066acdc30eddf1313382022-12-22T00:18:46ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-97412021-06-0136334635310.21470/1678-9741-2020-0618Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary AtherosclerosisMehmet Kaplanhttps://orcid.org/0000-0001-7081-5799Özge Özcan AbacıoğluFethi YavuzGizem Ilgın KaplanMustafa TopuzAbstract Introduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders and its prognosis is still debated. Objective: We aimed to review long-term follow-up data in patients with CAE and to evaluate the prognosis of CAE patients with coronary slow flow phenomenon (CSFP). Methods: This study had a prospective design and 143 patients with CAE were included. The angiographic and demographic characteristics were reviewed in detail. The patients were categorized, based on concomitant coronary artery stenosis detected by angiography, as CCAE group (n=87, ≥30% luminal stenosis) and ICAE group (n=56, <30% luminal stenosis) and also categorized by the coronary flow as CSFP group (n=51) and normal flow coronary ectasia - NCEA group (n=92). All patients were re-evaluated at 6-month intervals. Follow-up data, cardiovascular (CV) mortality, hospitalization and major adverse cardiac events (MACE) were collected. The level of statistical significance was set at 5%. Results: Patients were followed up for an average of 56.9±7.4 months. During the follow-up, statistically significant differences were found in hospitalization, CV mortality and MACE between the CCAE and ICAE groups (P=0.038, P=0.003, P=0.001, respectively). The CSFP and NCEA groups were also compared. There was a statistical difference with respect to hospitalization between the CFSP and NCEA groups (P=0.001), but no difference was observed in terms of MACE and CV mortality (P=0.793 and P=0.279). Conclusion: CSFP accompanying CAE may be a predictor of hospitalization. Significant atherosclerotic plaques coexisting with CAE may be predictive for MACE.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382021000300346&tlng=enCoronary Vessels. ConstrictionPathologic. Coronary Stenosis. Coronary Aneurysm. Angiography. Hospitalization
spellingShingle Mehmet Kaplan
Özge Özcan Abacıoğlu
Fethi Yavuz
Gizem Ilgın Kaplan
Mustafa Topuz
Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
Brazilian Journal of Cardiovascular Surgery
Coronary Vessels. Constriction
Pathologic. Coronary Stenosis. Coronary Aneurysm. Angiography. Hospitalization
title Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
title_full Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
title_fullStr Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
title_full_unstemmed Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
title_short Slow Flow Phenomenon Impairs the Prognosis of Coronary Artery Ectasia as Well as Coronary Atherosclerosis
title_sort slow flow phenomenon impairs the prognosis of coronary artery ectasia as well as coronary atherosclerosis
topic Coronary Vessels. Constriction
Pathologic. Coronary Stenosis. Coronary Aneurysm. Angiography. Hospitalization
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382021000300346&tlng=en
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