Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences

Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences

<p>Abstract</p> <p>Background</p> <p>DNA methylation has been linked to genome regulation and dysregulation in health and disease respectively, and methods for characterizing genomic DNA methylation patterns are rapidly emerging. We have developed/refined methods for en...

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Bibliographic Details
Main Authors: De Marzo Angelo M, Zheng Qizhi, Carvalho Benilton, Morgan James D, He Tony L, Badrinath Raghav, Aryee Martin J, Esopi David, Haffner Michael C, Wu Zhijin, Yegnasubramanian Srinivasan, Irizarry Rafael A, Nelson William G
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Genomics
Subjects:
DNA methylation
prostate cancer
tiling microarray
epigenetics
methylated DNA binding domain
MBD-chip
ADAMTS1
SCARF2
DSCR9
HLCS
Online Access:http://www.biomedcentral.com/1471-2164/12/313

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