Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study
Abstract Background Frailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France. We included 753 community-dwelling old participants with availab...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-022-03447-z |
| _version_ | 1818016828906012672 |
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| author | Achille Tchalla Cécile Laubarie-Mouret Noëlle Cardinaud Caroline Gayot Marion Rebiere Nathalie Dumoitier Karen Rudelle Michel Druet-Cabanac Marie-Laure Laroche Sophie Boyer |
| author_facet | Achille Tchalla Cécile Laubarie-Mouret Noëlle Cardinaud Caroline Gayot Marion Rebiere Nathalie Dumoitier Karen Rudelle Michel Druet-Cabanac Marie-Laure Laroche Sophie Boyer |
| author_sort | Achille Tchalla |
| collection | DOAJ |
| description | Abstract Background Frailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France. We included 753 community-dwelling old participants with available frailty data at baseline. Results Overall, 31.9% were frail, 58.3% were prefrail, and 9.8% were robust. The SMAF (French acronym for Functional Autonomy Measurement System) score was significantly lower (mean ± standard deviation: -25.8 ± 11.2) in frail participants compared to prefrail (-14.3 ± 9.7) or robust participants (-8.1 ± 7.0); 82% of frail older participants had limitation in at least one ADL and 97.5% in at least one IADL compared to 54.2 and 76.8%, respectively of pre-frail and 29.7 and 47.3% of robust participants. Age, depression, impaired cognition and diabetes were significantly associated with higher odds of frailty. These variables were also strongly associated with functional disability. Female gender, polypharmacy, and smoking were additional variables significantly associated with degraded SMAF and/or ADL/IADL. Conclusions This study showed that functional disability increased proportionally to frailty, and depression, cognitive decline and diabetes are modifiable risk factors significantly associated with frailty and functional disability. |
| first_indexed | 2024-04-14T07:18:38Z |
| format | Article |
| id | doaj.art-6cbed7d031fd400082479503851dc23d |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-14T07:18:38Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-6cbed7d031fd400082479503851dc23d2022-12-22T02:06:14ZengBMCBMC Geriatrics1471-23182022-09-012211910.1186/s12877-022-03447-zRisk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort studyAchille Tchalla0Cécile Laubarie-Mouret1Noëlle Cardinaud2Caroline Gayot3Marion Rebiere4Nathalie Dumoitier5Karen Rudelle6Michel Druet-Cabanac7Marie-Laure Laroche8Sophie Boyer9Laboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesLaboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesLaboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesLaboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesLaboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesCHU de Limoges, Pôle HU Gérontologie CliniqueCHU de Limoges, Pôle HU Gérontologie CliniqueCHU de Limoges, Pôle HU Gérontologie CliniqueCHU de Limoges, Pôle HU Gérontologie CliniqueLaboratoire VieSanté - UR 24134 (Vieillissement, Fragilité, Prévention, e-Santé), Institut OMEGA HEALTH, Université de LimogesAbstract Background Frailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France. We included 753 community-dwelling old participants with available frailty data at baseline. Results Overall, 31.9% were frail, 58.3% were prefrail, and 9.8% were robust. The SMAF (French acronym for Functional Autonomy Measurement System) score was significantly lower (mean ± standard deviation: -25.8 ± 11.2) in frail participants compared to prefrail (-14.3 ± 9.7) or robust participants (-8.1 ± 7.0); 82% of frail older participants had limitation in at least one ADL and 97.5% in at least one IADL compared to 54.2 and 76.8%, respectively of pre-frail and 29.7 and 47.3% of robust participants. Age, depression, impaired cognition and diabetes were significantly associated with higher odds of frailty. These variables were also strongly associated with functional disability. Female gender, polypharmacy, and smoking were additional variables significantly associated with degraded SMAF and/or ADL/IADL. Conclusions This study showed that functional disability increased proportionally to frailty, and depression, cognitive decline and diabetes are modifiable risk factors significantly associated with frailty and functional disability.https://doi.org/10.1186/s12877-022-03447-zAgingDependenceDisabilityFrailtyPhysical functioning |
| spellingShingle | Achille Tchalla Cécile Laubarie-Mouret Noëlle Cardinaud Caroline Gayot Marion Rebiere Nathalie Dumoitier Karen Rudelle Michel Druet-Cabanac Marie-Laure Laroche Sophie Boyer Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study BMC Geriatrics Aging Dependence Disability Frailty Physical functioning |
| title | Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study |
| title_full | Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study |
| title_fullStr | Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study |
| title_full_unstemmed | Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study |
| title_short | Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study |
| title_sort | risk factors of frailty and functional disability in community dwelling older adults a cross sectional analysis of the freedom lna cohort study |
| topic | Aging Dependence Disability Frailty Physical functioning |
| url | https://doi.org/10.1186/s12877-022-03447-z |
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