Leucine and perindopril to improve physical performance in people over 70 years with sarcopenia: the LACE factorial RCT

Leucine and perindopril to improve physical performance in people over 70 years with sarcopenia: the LACE factorial RCT

Background: Angiotensin-converting enzyme inhibitors and leucine are promising potential treatments for sarcopenia. Neither has yet been tested in adequately powered randomised trials in patients with sarcopenia. Objectives: To determine the efficacy of leucine and perindopril in improving physical...

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Bibliographic Details
Main Authors: Miles D Witham, Simon Adamson, Alison Avenell, Margaret M Band, Tufail Bashir, Peter T Donnan, Jacob George, Adrian Hapca, Cheryl Hume, Paul Kemp, Emma McKenzie, Kristina Pilvinyte, Christos Rossios, Karen Smith, Allan D Struthers, Deepa Sumukadas
Format: Article
Language:English
Published: NIHR Journals Library 2022-08-01
Series:Efficacy and Mechanism Evaluation
Subjects:
angiotensin-converting enzyme inhibitor
leucine
sarcopenia
randomised controlled trial
Online Access:https://doi.org/10.3310/LLBX6901

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