Epigenetic modification mechanism of histone demethylase KDM1A in regulating cardiomyocyte apoptosis after myocardial ischemia-reperfusion injury
Hypoxia and reoxygenation (H/R) play a prevalent role in heart-related diseases. Histone demethylases are involved in myocardial injury. In this study, the mechanism of the lysine-specific histone demethylase 1A (KDM1A/LSD1) on cardiomyocyte apoptosis after myocardial ischemia-reperfusion injury (MI...
Main Authors: | Lin He, Yanbo Wang, Jin Luo |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2022-08-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/13823.pdf |
Similar Items
-
Functions and Interactions of Mammalian KDM5 Demethylases
by: Egor Pavlenko, et al.
Published: (2022-07-01) -
Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target
by: Jung Yoo, et al.
Published: (2020-04-01) -
The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif
by: Xingyin Liu, et al.
Published: (2015-12-01) -
Small molecule KDM4s inhibitors as anti-cancer agents
by: Hongzhi Lin, et al.
Published: (2018-01-01) -
The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer
by: Dominic Jones, et al.
Published: (2019-08-01)