CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering

CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering

The Chinese hamster ovary (CHO) cell line is a well-established platform for the production of biopharmaceuticals due to its ability to express complex therapeutic proteins with human-like glycopatterns in high amounts. The advent of CRISPR technology has opened up new avenues for the engineering of...

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Bibliographic Details
Main Authors:	Katja Glinšek, Krištof Bozovičar, Tomaž Bratkovič
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	Chinese hamster ovary cells cell line development CRISPR-Cas genome editing glycoengineering augmenting productivity
Online Access:	https://www.mdpi.com/1422-0067/24/9/8144

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