Sterile triggers drive joint inflammation in TNF‐ and IL‐1β‐dependent mouse arthritis models

Sterile triggers drive joint inflammation in TNF‐ and IL‐1β‐dependent mouse arthritis models

Abstract Arthritis is the most common extra‐intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shared disease etiology, commonly termed “the gut‐joint‐...

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Bibliographic Details
Main Authors: Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, Tino Hochepied, Christian Vanhove, Eric Gracey, Emilie Dumas, Teddy Manuelo, Ivan Josipovic, Geert vanLoo, Dirk Elewaut, Lars Vereecke
Format: Article
Language:English
Published: Springer Nature 2023-10-01
Series:EMBO Molecular Medicine
Subjects:
arthritis
germ‐free
gut‐joint axis
intestinal inflammation
microbiome
Online Access:https://doi.org/10.15252/emmm.202317691

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