Intestinal fibrogenesis in inflammatory intestinal disorders
The article deals with chronic inflammatory processes of the intestines and their complications that contribute to the gradual accumulation of deep transmural lesions of the intestinal wall, including narrowings, development of obstruction, abscesses, and fistulas. Both inflammatory bowel diseases a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaslavsky O.Yu.
2022-12-01
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| Series: | Gastroenterologìa |
| Subjects: | |
| Online Access: | https://gastro.zaslavsky.com.ua/index.php/journal/article/view/518 |
| _version_ | 1827932663567089664 |
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| author | М.М. Zhaivoronok V.N. Zalessky |
| author_facet | М.М. Zhaivoronok V.N. Zalessky |
| author_sort | М.М. Zhaivoronok |
| collection | DOAJ |
| description | The article deals with chronic inflammatory processes of the intestines and their complications that contribute to the gradual accumulation of deep transmural lesions of the intestinal wall, including narrowings, development of obstruction, abscesses, and fistulas. Both inflammatory bowel diseases and their chronic complications lead to the onset of diarrhea, abdominal pain, anemia caused by intestinal pathology. Detecting the disease activity and complications severity is of crucial importance in the treatment intensity at early and later stages of the illness and when monitoring treatment measures effectiveness. The main molecular mediators of fibrogenesis are studied in the article, the results of development of intestinal fibrosis visualization technologies are summarized, possibilities for expanding the quantitative magnetic resonance imaging, computed tomography, ultrasound and encouraging potential of non-invasive elastography methods are discussed. |
| first_indexed | 2024-03-13T07:12:58Z |
| format | Article |
| id | doaj.art-6cc723dc087c4929bcbef973f3263c85 |
| institution | Directory Open Access Journal |
| issn | 2308-2097 2518-7880 |
| language | English |
| last_indexed | 2024-03-13T07:12:58Z |
| publishDate | 2022-12-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Gastroenterologìa |
| spelling | doaj.art-6cc723dc087c4929bcbef973f3263c852023-06-05T18:35:38ZengZaslavsky O.Yu.Gastroenterologìa2308-20972518-78802022-12-0156425826510.22141/2308-2097.56.4.2022.518518Intestinal fibrogenesis in inflammatory intestinal disordersМ.М. Zhaivoronok0https://orcid.org/0000-0001-9237-1412V.N. Zalessky1Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine; Medical Scientific and Practical Association “MedBud”, Kyiv, UkraineState Institution “National Scientific Center “M.D. Strazhesko Institute of Cardiology of the National Academy of Medical Sciences of Ukraine”, Kyiv, UkraineThe article deals with chronic inflammatory processes of the intestines and their complications that contribute to the gradual accumulation of deep transmural lesions of the intestinal wall, including narrowings, development of obstruction, abscesses, and fistulas. Both inflammatory bowel diseases and their chronic complications lead to the onset of diarrhea, abdominal pain, anemia caused by intestinal pathology. Detecting the disease activity and complications severity is of crucial importance in the treatment intensity at early and later stages of the illness and when monitoring treatment measures effectiveness. The main molecular mediators of fibrogenesis are studied in the article, the results of development of intestinal fibrosis visualization technologies are summarized, possibilities for expanding the quantitative magnetic resonance imaging, computed tomography, ultrasound and encouraging potential of non-invasive elastography methods are discussed.https://gastro.zaslavsky.com.ua/index.php/journal/article/view/518intestinal fibrosiscrohn’s diseaseulcerative colitismolecular mechanismsbiomarkersimaging methodsmagnetic resonance imagingcomputed tomographyultrasoundelastography |
| spellingShingle | М.М. Zhaivoronok V.N. Zalessky Intestinal fibrogenesis in inflammatory intestinal disorders Gastroenterologìa intestinal fibrosis crohn’s disease ulcerative colitis molecular mechanisms biomarkers imaging methods magnetic resonance imaging computed tomography ultrasound elastography |
| title | Intestinal fibrogenesis in inflammatory intestinal disorders |
| title_full | Intestinal fibrogenesis in inflammatory intestinal disorders |
| title_fullStr | Intestinal fibrogenesis in inflammatory intestinal disorders |
| title_full_unstemmed | Intestinal fibrogenesis in inflammatory intestinal disorders |
| title_short | Intestinal fibrogenesis in inflammatory intestinal disorders |
| title_sort | intestinal fibrogenesis in inflammatory intestinal disorders |
| topic | intestinal fibrosis crohn’s disease ulcerative colitis molecular mechanisms biomarkers imaging methods magnetic resonance imaging computed tomography ultrasound elastography |
| url | https://gastro.zaslavsky.com.ua/index.php/journal/article/view/518 |
| work_keys_str_mv | AT mmzhaivoronok intestinalfibrogenesisininflammatoryintestinaldisorders AT vnzalessky intestinalfibrogenesisininflammatoryintestinaldisorders |