Advanced Waveguide Based LOC Biosensors: A Minireview

This mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms...

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Main Authors: Muzafar A. Kanjwal, Amal Al Ghaferi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/14/5443
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author Muzafar A. Kanjwal
Amal Al Ghaferi
author_facet Muzafar A. Kanjwal
Amal Al Ghaferi
author_sort Muzafar A. Kanjwal
collection DOAJ
description This mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms will soon supplement the current sensing technologies for biomedical diagnostics. The state-of-the-art shows that various types of waveguide material can be utilized for waveguide spectroscopic measurements in MIR. However, there are challenges to integrating these waveguide platforms with microfluidic/Lab-on-a-Chip (LOC) devices, due to poor light–material interactions. Graphene and its analogs have found many applications in microfluidic-based LOC devices, to address to this issue. Graphene-based materials possess a high conductivity, a large surface-to-volume ratio, a smaller and tunable bandgap, and allow easier sample loading; which is essential for acquiring precise electrochemical information. This work discusses advanced waveguide materials, their advantages, and disease diagnostics with MIR thin-film based waveguides. The incorporation of graphene into waveguides improves the light–graphene interaction, and photonic devices greatly benefit from graphene’s strong field-controlled optical response.
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spelling doaj.art-6cc87d4410924267b8562392273dc6b32023-12-01T22:41:07ZengMDPI AGSensors1424-82202022-07-012214544310.3390/s22145443Advanced Waveguide Based LOC Biosensors: A MinireviewMuzafar A. Kanjwal0Amal Al Ghaferi1Mechanical Engineering Department, Khalifa University, Abu Dhabi 127788, United Arab EmiratesMechanical Engineering Department, Khalifa University, Abu Dhabi 127788, United Arab EmiratesThis mini review features contemporary advances in mid-infrared (MIR) thin-film waveguide technology and on-chip photonics, promoting high-performance biosensing platforms. Supported by recent developments in MIR thin-film waveguides, it is expected that label-free assimilated MIR sensing platforms will soon supplement the current sensing technologies for biomedical diagnostics. The state-of-the-art shows that various types of waveguide material can be utilized for waveguide spectroscopic measurements in MIR. However, there are challenges to integrating these waveguide platforms with microfluidic/Lab-on-a-Chip (LOC) devices, due to poor light–material interactions. Graphene and its analogs have found many applications in microfluidic-based LOC devices, to address to this issue. Graphene-based materials possess a high conductivity, a large surface-to-volume ratio, a smaller and tunable bandgap, and allow easier sample loading; which is essential for acquiring precise electrochemical information. This work discusses advanced waveguide materials, their advantages, and disease diagnostics with MIR thin-film based waveguides. The incorporation of graphene into waveguides improves the light–graphene interaction, and photonic devices greatly benefit from graphene’s strong field-controlled optical response.https://www.mdpi.com/1424-8220/22/14/5443mid-infraredwaveguidesLOC devicesgraphene incorporation
spellingShingle Muzafar A. Kanjwal
Amal Al Ghaferi
Advanced Waveguide Based LOC Biosensors: A Minireview
Sensors
mid-infrared
waveguides
LOC devices
graphene incorporation
title Advanced Waveguide Based LOC Biosensors: A Minireview
title_full Advanced Waveguide Based LOC Biosensors: A Minireview
title_fullStr Advanced Waveguide Based LOC Biosensors: A Minireview
title_full_unstemmed Advanced Waveguide Based LOC Biosensors: A Minireview
title_short Advanced Waveguide Based LOC Biosensors: A Minireview
title_sort advanced waveguide based loc biosensors a minireview
topic mid-infrared
waveguides
LOC devices
graphene incorporation
url https://www.mdpi.com/1424-8220/22/14/5443
work_keys_str_mv AT muzafarakanjwal advancedwaveguidebasedlocbiosensorsaminireview
AT amalalghaferi advancedwaveguidebasedlocbiosensorsaminireview