Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2020.588384/full |
| _version_ | 1818385065489465344 |
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| author | Andrea Montesel Claudio Bucolo Victoria Mouvet Emmanuelle Moret Chiara M. Eandi |
| author_facet | Andrea Montesel Claudio Bucolo Victoria Mouvet Emmanuelle Moret Chiara M. Eandi |
| author_sort | Andrea Montesel |
| collection | DOAJ |
| description | We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system. |
| first_indexed | 2024-12-14T03:32:14Z |
| format | Article |
| id | doaj.art-6cc9287d0e0145a59c43cb845731736f |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-14T03:32:14Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-6cc9287d0e0145a59c43cb845731736f2022-12-21T23:18:44ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-12-011110.3389/fphar.2020.588384588384Case Report: Central Retinal Artery Occlusion in a COVID-19 PatientAndrea Montesel0Claudio Bucolo1Victoria Mouvet2Emmanuelle Moret3Chiara M. Eandi4Department of Ophthalmology, Fondation Asile des Aveugles, Jules Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandDepartment of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, Catania, ItalyDepartment of Ophthalmology, Fondation Asile des Aveugles, Jules Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandDepartment of Ophthalmology, Fondation Asile des Aveugles, Jules Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandDepartment of Ophthalmology, Fondation Asile des Aveugles, Jules Gonin Eye Hospital, University of Lausanne, Lausanne, SwitzerlandWe report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system.https://www.frontiersin.org/articles/10.3389/fphar.2020.588384/fullsevere acute respiratory syndrome coronavirus 2coronavirus disease-2019central retinal artery occlusionthrombosiscase reportSARS-CoV-2 |
| spellingShingle | Andrea Montesel Claudio Bucolo Victoria Mouvet Emmanuelle Moret Chiara M. Eandi Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient Frontiers in Pharmacology severe acute respiratory syndrome coronavirus 2 coronavirus disease-2019 central retinal artery occlusion thrombosis case report SARS-CoV-2 |
| title | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
| title_full | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
| title_fullStr | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
| title_full_unstemmed | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
| title_short | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
| title_sort | case report central retinal artery occlusion in a covid 19 patient |
| topic | severe acute respiratory syndrome coronavirus 2 coronavirus disease-2019 central retinal artery occlusion thrombosis case report SARS-CoV-2 |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2020.588384/full |
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