Evaluating the association between DNM1L variants and Parkinson's disease in the Chinese population

Evaluating the association between DNM1L variants and Parkinson's disease in the Chinese population

IntroductionParkinson's disease (PD) is a progressive movement disorder caused by a loss of dopaminergic neurons. Previous studies have highlighted the importance of mitochondria dynamics in the pathogenesis of PD. Dynamin-1-like (DNM1L) is a gene that encodes dynamin-related protein 1 (DRP1),...

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Bibliographic Details
Main Authors: Jiabin Liu, Juanjuan Huang, Yuwen Zhao, Hongxu Pan, Yige Wang, Zhenhua Liu, Qian Xu, Qiying Sun, Jieqiong Tan, Xinxiang Yan, Jinchen Li, Beisha Tang, Jifeng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
DNM1L
DRP1
mitochondria
rare variants
common variants
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1133449/full

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