Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts
Abstract Background Sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of...
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| Format: | Article |
| Language: | English |
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BMC
2019-06-01
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| Series: | BMC Complementary and Alternative Medicine |
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| Online Access: | http://link.springer.com/article/10.1186/s12906-019-2564-y |
| _version_ | 1819012592814784512 |
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| author | Bartosz Skalski Bogdan Kontek Bernadetta Lis Beata Olas Łukasz Grabarczyk Anna Stochmal Jerzy Żuchowski |
| author_facet | Bartosz Skalski Bogdan Kontek Bernadetta Lis Beata Olas Łukasz Grabarczyk Anna Stochmal Jerzy Żuchowski |
| author_sort | Bartosz Skalski |
| collection | DOAJ |
| description | Abstract Background Sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of this plant (both fresh and dried) contain a lot of nutrients and bioactive compounds, including phenolic compounds. The present study was carried out in order to investigate antioxidant and anticoagulant properties of sea buckthorn twig and leaf extracts (0.5–50 μg/mL) by using various in vitro models. Moreover, the aim of present experiments was to compare the biological activity of SBT leaf extract and SBT twig extract with selected berry extracts (a rich source of phenolic compounds): SBT berry extract (flavonoids being the dominant components), a commercial extract from the berries of Aronia melanocarpa (Aronox®), and a grape seed extract. Methods We determined the effect of plant extracts on the oxidative stress using selected markers of this process, i.e. the level of carbonyl groups in proteins. Additionally, we analysed the potential mechanism of modulation of hemostatic properties of human plasma (using selected coagulation times). Results SBT twig and leaf extracts were observed to exhibit an antioxidant activity against two strong biological oxidants: hydrogen peroxide (H2O2) and H2O2/Fe (the donor of hydroxyl radicals), which induced human plasma lipid peroxidation and protein carbonylation. Both extracts also showed anticoagulant properties. Conclusions Our present results have demonstrated that extracts from different parts of SBT, especially berries and twigs, in comparison to well-known berries (aronia and grape), may also be viewed as a good source of active substances – antioxidants for pharmacological or cosmetic applications. Moreover, it is very important from an economic point of view to know that there is a possibility of obtaining phenolic compounds not only from the berries or leaves, but also from twigs, which constitute a production waste. |
| first_indexed | 2024-12-21T01:46:30Z |
| format | Article |
| id | doaj.art-6ccd8dd219cd4bdc8b49585b3e60ca57 |
| institution | Directory Open Access Journal |
| issn | 1472-6882 |
| language | English |
| last_indexed | 2024-12-21T01:46:30Z |
| publishDate | 2019-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary and Alternative Medicine |
| spelling | doaj.art-6ccd8dd219cd4bdc8b49585b3e60ca572022-12-21T19:20:01ZengBMCBMC Complementary and Alternative Medicine1472-68822019-06-0119111210.1186/s12906-019-2564-yBiological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extractsBartosz Skalski0Bogdan Kontek1Bernadetta Lis2Beata Olas3Łukasz Grabarczyk4Anna Stochmal5Jerzy Żuchowski6Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of ŁódźDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of ŁódźDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of ŁódźDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of ŁódźDepartment of Neurology and Neurosurgery, Faculty of Medical Sciences, University of Warmia and MazuryDepartment of Biochemistry, Institute of Soil Science and Plant Cultivation, State Research InstituteDepartment of Biochemistry, Institute of Soil Science and Plant Cultivation, State Research InstituteAbstract Background Sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of this plant (both fresh and dried) contain a lot of nutrients and bioactive compounds, including phenolic compounds. The present study was carried out in order to investigate antioxidant and anticoagulant properties of sea buckthorn twig and leaf extracts (0.5–50 μg/mL) by using various in vitro models. Moreover, the aim of present experiments was to compare the biological activity of SBT leaf extract and SBT twig extract with selected berry extracts (a rich source of phenolic compounds): SBT berry extract (flavonoids being the dominant components), a commercial extract from the berries of Aronia melanocarpa (Aronox®), and a grape seed extract. Methods We determined the effect of plant extracts on the oxidative stress using selected markers of this process, i.e. the level of carbonyl groups in proteins. Additionally, we analysed the potential mechanism of modulation of hemostatic properties of human plasma (using selected coagulation times). Results SBT twig and leaf extracts were observed to exhibit an antioxidant activity against two strong biological oxidants: hydrogen peroxide (H2O2) and H2O2/Fe (the donor of hydroxyl radicals), which induced human plasma lipid peroxidation and protein carbonylation. Both extracts also showed anticoagulant properties. Conclusions Our present results have demonstrated that extracts from different parts of SBT, especially berries and twigs, in comparison to well-known berries (aronia and grape), may also be viewed as a good source of active substances – antioxidants for pharmacological or cosmetic applications. Moreover, it is very important from an economic point of view to know that there is a possibility of obtaining phenolic compounds not only from the berries or leaves, but also from twigs, which constitute a production waste.http://link.springer.com/article/10.1186/s12906-019-2564-yOxidative stressElaeagnus rhamnoides (L.) a. NelsonTwigLeafBerryPhenolic compounds |
| spellingShingle | Bartosz Skalski Bogdan Kontek Bernadetta Lis Beata Olas Łukasz Grabarczyk Anna Stochmal Jerzy Żuchowski Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts BMC Complementary and Alternative Medicine Oxidative stress Elaeagnus rhamnoides (L.) a. Nelson Twig Leaf Berry Phenolic compounds |
| title | Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts |
| title_full | Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts |
| title_fullStr | Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts |
| title_full_unstemmed | Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts |
| title_short | Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts |
| title_sort | biological properties of elaeagnus rhamnoides l a nelson twig and leaf extracts |
| topic | Oxidative stress Elaeagnus rhamnoides (L.) a. Nelson Twig Leaf Berry Phenolic compounds |
| url | http://link.springer.com/article/10.1186/s12906-019-2564-y |
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