Electrogenerated chemiluminescence peptide-based bioassay

Electrogenerated chemiluminescence (ECL) involves the generation of species at electrode surfaces that then undergo electron-transfer reactions to form excited states that emit light. The ECL method is becoming an increasingly promising method in the life sciences, environmental analysis, and clinic...

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Main Authors: Qi Honglan, Dang Qian, Dong Manman, Gao Hongfang, Li Min
Format: Article
Language:English
Published: De Gruyter 2014-12-01
Series:Reviews in Analytical Chemistry
Subjects:
Online Access:https://doi.org/10.1515/revac-2014-0015
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author Qi Honglan
Dang Qian
Dong Manman
Gao Hongfang
Li Min
author_facet Qi Honglan
Dang Qian
Dong Manman
Gao Hongfang
Li Min
author_sort Qi Honglan
collection DOAJ
description Electrogenerated chemiluminescence (ECL) involves the generation of species at electrode surfaces that then undergo electron-transfer reactions to form excited states that emit light. The ECL method is becoming an increasingly promising method in the life sciences, environmental analysis, and clinical analysis, owing to its good selectivity, high sensitivity, wide dynamic concentration response range, and potential and spatial controllability. Here, we give a mini-review on the advances of the ECL peptide-based bioassay using peptide as the molecular recognition element. First, a general history of ECL development is presented. Then, the general strategies of the ECL peptide-based bioassay are reviewed. Particular attention is paid to the related progress in the last 5 years. Finally, we conclude with the future challenges and prospects in the development of the ECL peptide-based bioassay.
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spelling doaj.art-6cd121fb5b2e4342b275d5c1e5a19b102022-12-21T22:48:23ZengDe GruyterReviews in Analytical Chemistry0793-01352191-01892014-12-0133425526310.1515/revac-2014-0015Electrogenerated chemiluminescence peptide-based bioassayQi Honglan0Dang Qian1Dong Manman2Gao Hongfang3Li Min4Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, P.R. ChinaKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, P.R. ChinaKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, P.R. ChinaKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, P.R. ChinaKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, P.R. ChinaElectrogenerated chemiluminescence (ECL) involves the generation of species at electrode surfaces that then undergo electron-transfer reactions to form excited states that emit light. The ECL method is becoming an increasingly promising method in the life sciences, environmental analysis, and clinical analysis, owing to its good selectivity, high sensitivity, wide dynamic concentration response range, and potential and spatial controllability. Here, we give a mini-review on the advances of the ECL peptide-based bioassay using peptide as the molecular recognition element. First, a general history of ECL development is presented. Then, the general strategies of the ECL peptide-based bioassay are reviewed. Particular attention is paid to the related progress in the last 5 years. Finally, we conclude with the future challenges and prospects in the development of the ECL peptide-based bioassay.https://doi.org/10.1515/revac-2014-0015bioassayelectrogenerated chemiluminescencepeptide
spellingShingle Qi Honglan
Dang Qian
Dong Manman
Gao Hongfang
Li Min
Electrogenerated chemiluminescence peptide-based bioassay
Reviews in Analytical Chemistry
bioassay
electrogenerated chemiluminescence
peptide
title Electrogenerated chemiluminescence peptide-based bioassay
title_full Electrogenerated chemiluminescence peptide-based bioassay
title_fullStr Electrogenerated chemiluminescence peptide-based bioassay
title_full_unstemmed Electrogenerated chemiluminescence peptide-based bioassay
title_short Electrogenerated chemiluminescence peptide-based bioassay
title_sort electrogenerated chemiluminescence peptide based bioassay
topic bioassay
electrogenerated chemiluminescence
peptide
url https://doi.org/10.1515/revac-2014-0015
work_keys_str_mv AT qihonglan electrogeneratedchemiluminescencepeptidebasedbioassay
AT dangqian electrogeneratedchemiluminescencepeptidebasedbioassay
AT dongmanman electrogeneratedchemiluminescencepeptidebasedbioassay
AT gaohongfang electrogeneratedchemiluminescencepeptidebasedbioassay
AT limin electrogeneratedchemiluminescencepeptidebasedbioassay