Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury

Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury

Summary: The transcriptome analysis of injured Xenopus laevis tadpole and mice suggested that Neurod4L.S., a basic-helix-loop-helix transcription factor, was the most promising transcription factor to exert neuroregeneration after spinal cord injury (SCI) in mammals. We generated a pseudotyped retro...

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Bibliographic Details
Main Authors: Toshiki Fukuoka, Akira Kato, Masaki Hirano, Fumiharu Ohka, Kosuke Aoki, Takayuki Awaya, Alimu Adilijiang, Maeda Sachi, Kuniaki Tanahashi, Junya Yamaguchi, Kazuya Motomura, Hiroyuki Shimizu, Yoshitaka Nagashima, Ryo Ando, Toshihiko Wakabayashi, Dasfne Lee-Liu, Juan Larrain, Yusuke Nishimura, Atsushi Natsume
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Biological Sciences
Neuroscience
Behavioral Neuroscience
Cellular Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000420

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