High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis
Abstract Background Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria and can be used as vaccines. Often, detergents are used to promote release of OMVs and to remove the toxic lipopolysaccharides. Lipopolysaccharides can be detoxified by genetic modification such t...
Main Authors: | Matthias J. H. Gerritzen, Ronald H. W. Maas, Jan van den Ijssel, Lonneke van Keulen, Dirk E. Martens, René H. Wijffels, Michiel Stork |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-018-1007-7 |
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