Nrf2-activating Therapy Accelerates Wound Healing in a Model of Cutaneous Chronic Venous Insufficiency
Background. Chronic venous insufficiency (CVI) stems from venous hypertension, extravasation of blood, and iron-rich skin deposits. The latter is central to ulcer development through generating reactive oxygen species (ROS) that drive persistent local inflammation and the development of lipodermatos...
Main Authors: | Joseph Kuhn, MD, Darren L. Sultan, MD, Bukhtawar Waqas, BA, Trevor Ellison, MD, Jennifer Kwong, BA, Camille Kim, DPM, Absara Hassan, Piul S. Rabbani, PhD, Daniel J. Ceradini, MD |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2020-11-01
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Series: | Plastic and Reconstructive Surgery, Global Open |
Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003006 |
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