Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a frequent, often progressive, chronic disease of the lungs. Patients with COPD often have impaired immunity; therefore, they are prone to chest infections, such as pneumonia or bronchitis. Acute exacerbations of COPD are major events that accelerate d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/12/2/213 |
| _version_ | 1827342613676556288 |
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| author | Dóra Paróczai Katalin Burian Andras Bikov |
| author_facet | Dóra Paróczai Katalin Burian Andras Bikov |
| author_sort | Dóra Paróczai |
| collection | DOAJ |
| description | Chronic obstructive pulmonary disease (COPD) is a frequent, often progressive, chronic disease of the lungs. Patients with COPD often have impaired immunity; therefore, they are prone to chest infections, such as pneumonia or bronchitis. Acute exacerbations of COPD are major events that accelerate disease progression, contributing to its symptoms’ burden, morbidity, and mortality. Both pneumonia and acute exacerbations in COPD are caused by bacteria against which there are effective vaccinations. Although the number of randomised controlled studies on bacterial vaccinations in COPD is limited, national and international guidelines endorse specific vaccinations in patients with COPD. This review will summarise the different types of vaccinations that prevent pneumonia and COPD exacerbations. We also discuss the results of early phase studies. We will mainly focus on <i>Streptococcus pneumoniae</i>, as this bacterium was predominantly investigated in COPD. However, we also review studies investigating vaccinations against <i>Haemophilus influenzae</i>, <i>Moraxella catarrhalis</i>, and <i>Bordetella pertussis</i>. |
| first_indexed | 2024-03-07T22:11:04Z |
| format | Article |
| id | doaj.art-6ce3587b08cc46c4b59c7a7c9123e77a |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-07T22:11:04Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-6ce3587b08cc46c4b59c7a7c9123e77a2024-02-23T15:37:12ZengMDPI AGVaccines2076-393X2024-02-0112221310.3390/vaccines12020213Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary DiseaseDóra Paróczai0Katalin Burian1Andras Bikov2Department of Medical Microbiology, University of Szeged, H-6720 Szeged, HungaryDepartment of Medical Microbiology, University of Szeged, H-6720 Szeged, HungaryManchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester M23 9LT, UKChronic obstructive pulmonary disease (COPD) is a frequent, often progressive, chronic disease of the lungs. Patients with COPD often have impaired immunity; therefore, they are prone to chest infections, such as pneumonia or bronchitis. Acute exacerbations of COPD are major events that accelerate disease progression, contributing to its symptoms’ burden, morbidity, and mortality. Both pneumonia and acute exacerbations in COPD are caused by bacteria against which there are effective vaccinations. Although the number of randomised controlled studies on bacterial vaccinations in COPD is limited, national and international guidelines endorse specific vaccinations in patients with COPD. This review will summarise the different types of vaccinations that prevent pneumonia and COPD exacerbations. We also discuss the results of early phase studies. We will mainly focus on <i>Streptococcus pneumoniae</i>, as this bacterium was predominantly investigated in COPD. However, we also review studies investigating vaccinations against <i>Haemophilus influenzae</i>, <i>Moraxella catarrhalis</i>, and <i>Bordetella pertussis</i>.https://www.mdpi.com/2076-393X/12/2/213COPDvaccinationbacteria |
| spellingShingle | Dóra Paróczai Katalin Burian Andras Bikov Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease Vaccines COPD vaccination bacteria |
| title | Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease |
| title_full | Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease |
| title_fullStr | Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease |
| title_short | Bacterial Vaccinations in Patients with Chronic Obstructive Pulmonary Disease |
| title_sort | bacterial vaccinations in patients with chronic obstructive pulmonary disease |
| topic | COPD vaccination bacteria |
| url | https://www.mdpi.com/2076-393X/12/2/213 |
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