Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis
Background and Aim: Oral drugs and nonsteroidal anti-inflammatory drugs which are used to relieve pain are associated with certain side effects in the patients with knee osteoarthritis. The aim of this study was to compare the effects of a herbal drug, Zingiber officinale jelly, and piroxicam jelly...
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| Format: | Article |
| Language: | fas |
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Kurdistan University of Medical Sciences
2018-04-01
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| Series: | مجله علمی دانشگاه علوم پزشکی کردستان |
| Subjects: | |
| Online Access: | http://sjku.muk.ac.ir/article-1-3906-en.html |
| _version_ | 1818293517549568000 |
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| author | Morteza Dehghan Abbas Abdoli-tafti Foroozan Ganji Rasoul Ghaedi |
| author_facet | Morteza Dehghan Abbas Abdoli-tafti Foroozan Ganji Rasoul Ghaedi |
| author_sort | Morteza Dehghan |
| collection | DOAJ |
| description | Background and Aim: Oral drugs and nonsteroidal anti-inflammatory drugs which are used to relieve pain are associated with certain side effects in the patients with knee osteoarthritis. The aim of this study was to compare the effects of a herbal drug, Zingiber officinale jelly, and piroxicam jelly on pain relief, morning stiffness, and physical performance in the patients with knee osteoarthritis.
Material and Methods: In this semi-experimental study one hundred and twenty patients with osteoarthritis were randomly assigned to three groups of 40. Z. officinale 2% jelly, piroxicam jelly, and placebo were given twice a day for 14 days to the 1st, 2nd and 3rd groups respectively. Concurrently, diclofenac tablet 100mg/ day was given to all groups. Physical examination was performed before intervention and two weeks after completion of the treatment. The level of pain was measured by use of visual analogue scale. Furthermore, the WOMAC index was used to investigate the effect of pain on the patientschr('39') performance. Using SPSS software, data were analyzed by paired t-test, chi-square and ANOVA.
Result: There were no significant difference between Z. officinale jelly and piroxicam jelly in relation to relief of overall pain and morning stiffness, (P>0.05). The relief of pain (P=0.01) and morning stiffness (P=0.002) were significantly more marked in the piroxicam-treated group compared to those in the placebo group. Improvement of the physical functioning was not significantly different between the piroxicam-treated and Z. officinale-treated groups (P>0.05).
Conclusion: Z. officinale jelly and piroxicam jelly were effective in pain relief, amelioration of morning stiffness, and improvement of physical functioning in the patients with knee osteoarthritis, and there were no significant differences between the effects of the jellies.
Key words: Osteoarthritis, Ginger jelly, Piroxicam jelly.
Received: Jun 28, 2017 Accepted: Jan 8, 2018 |
| first_indexed | 2024-12-13T03:17:07Z |
| format | Article |
| id | doaj.art-6ce894c20e0b4f46b2e6a45f6067a802 |
| institution | Directory Open Access Journal |
| issn | 1560-652X 2345-4040 |
| language | fas |
| last_indexed | 2024-12-13T03:17:07Z |
| publishDate | 2018-04-01 |
| publisher | Kurdistan University of Medical Sciences |
| record_format | Article |
| series | مجله علمی دانشگاه علوم پزشکی کردستان |
| spelling | doaj.art-6ce894c20e0b4f46b2e6a45f6067a8022022-12-22T00:01:27ZfasKurdistan University of Medical Sciencesمجله علمی دانشگاه علوم پزشکی کردستان1560-652X2345-40402018-04-01231817Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritisMorteza Dehghan0Abbas Abdoli-tafti1Foroozan Ganji2Rasoul Ghaedi3 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran. Orthopedic Surgery Dept, Shahrekord University of Medical Sciences, Shahrekord, Iran Social Medicine Dept, Shahrekord University of Medical Sciences, Shahrekord Iran. Shahrekord University of Medical Sciences, Shahrekord, Iran. Background and Aim: Oral drugs and nonsteroidal anti-inflammatory drugs which are used to relieve pain are associated with certain side effects in the patients with knee osteoarthritis. The aim of this study was to compare the effects of a herbal drug, Zingiber officinale jelly, and piroxicam jelly on pain relief, morning stiffness, and physical performance in the patients with knee osteoarthritis. Material and Methods: In this semi-experimental study one hundred and twenty patients with osteoarthritis were randomly assigned to three groups of 40. Z. officinale 2% jelly, piroxicam jelly, and placebo were given twice a day for 14 days to the 1st, 2nd and 3rd groups respectively. Concurrently, diclofenac tablet 100mg/ day was given to all groups. Physical examination was performed before intervention and two weeks after completion of the treatment. The level of pain was measured by use of visual analogue scale. Furthermore, the WOMAC index was used to investigate the effect of pain on the patientschr('39') performance. Using SPSS software, data were analyzed by paired t-test, chi-square and ANOVA. Result: There were no significant difference between Z. officinale jelly and piroxicam jelly in relation to relief of overall pain and morning stiffness, (P>0.05). The relief of pain (P=0.01) and morning stiffness (P=0.002) were significantly more marked in the piroxicam-treated group compared to those in the placebo group. Improvement of the physical functioning was not significantly different between the piroxicam-treated and Z. officinale-treated groups (P>0.05). Conclusion: Z. officinale jelly and piroxicam jelly were effective in pain relief, amelioration of morning stiffness, and improvement of physical functioning in the patients with knee osteoarthritis, and there were no significant differences between the effects of the jellies. Key words: Osteoarthritis, Ginger jelly, Piroxicam jelly. Received: Jun 28, 2017 Accepted: Jan 8, 2018http://sjku.muk.ac.ir/article-1-3906-en.htmlosteoarthritisginger jellypiroxicam jelly. |
| spellingShingle | Morteza Dehghan Abbas Abdoli-tafti Foroozan Ganji Rasoul Ghaedi Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis مجله علمی دانشگاه علوم پزشکی کردستان osteoarthritis ginger jelly piroxicam jelly. |
| title | Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis |
| title_full | Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis |
| title_fullStr | Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis |
| title_full_unstemmed | Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis |
| title_short | Comparison the effects of ginger (Zingiber officinale) jelly and piroxicam jelly on pain of knee osteoarthritis |
| title_sort | comparison the effects of ginger zingiber officinale jelly and piroxicam jelly on pain of knee osteoarthritis |
| topic | osteoarthritis ginger jelly piroxicam jelly. |
| url | http://sjku.muk.ac.ir/article-1-3906-en.html |
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