A quadratic model captures the human V1 response to variations in chromatic direction and contrast
An important goal for vision science is to develop quantitative models of the representation of visual signals at post-receptoral sites. To this end, we develop the quadratic color model (QCM) and examine its ability to account for the BOLD fMRI response in human V1 to spatially uniform, temporal ch...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2021-08-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/65590 |
| _version_ | 1811253310574821376 |
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| author | Michael A Barnett Geoffrey K Aguirre David Brainard |
| author_facet | Michael A Barnett Geoffrey K Aguirre David Brainard |
| author_sort | Michael A Barnett |
| collection | DOAJ |
| description | An important goal for vision science is to develop quantitative models of the representation of visual signals at post-receptoral sites. To this end, we develop the quadratic color model (QCM) and examine its ability to account for the BOLD fMRI response in human V1 to spatially uniform, temporal chromatic modulations that systematically vary in chromatic direction and contrast. We find that the QCM explains the same, cross-validated variance as a conventional general linear model, with far fewer free parameters. The QCM generalizes to allow prediction of V1 responses to a large range of modulations. We replicate the results for each subject and find good agreement across both replications and subjects. We find that within the LM cone contrast plane, V1 is most sensitive to L-M contrast modulations and least sensitive to L+M contrast modulations. Within V1, we observe little to no change in chromatic sensitivity as a function of eccentricity. |
| first_indexed | 2024-04-12T16:48:55Z |
| format | Article |
| id | doaj.art-6cee8d46d5cf4371b372d65c6fcfad10 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T16:48:55Z |
| publishDate | 2021-08-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-6cee8d46d5cf4371b372d65c6fcfad102022-12-22T03:24:28ZengeLife Sciences Publications LtdeLife2050-084X2021-08-011010.7554/eLife.65590A quadratic model captures the human V1 response to variations in chromatic direction and contrastMichael A Barnett0https://orcid.org/0000-0002-8355-4601Geoffrey K Aguirre1https://orcid.org/0000-0002-4028-3100David Brainard2https://orcid.org/0000-0001-9827-543XDepartment of Psychology, University of Pennsylvania, Philadelphia, United StatesDepartment of Neurology, University of Pennsylvania, Philadelphia, United StatesDepartment of Psychology, University of Pennsylvania, Philadelphia, United StatesAn important goal for vision science is to develop quantitative models of the representation of visual signals at post-receptoral sites. To this end, we develop the quadratic color model (QCM) and examine its ability to account for the BOLD fMRI response in human V1 to spatially uniform, temporal chromatic modulations that systematically vary in chromatic direction and contrast. We find that the QCM explains the same, cross-validated variance as a conventional general linear model, with far fewer free parameters. The QCM generalizes to allow prediction of V1 responses to a large range of modulations. We replicate the results for each subject and find good agreement across both replications and subjects. We find that within the LM cone contrast plane, V1 is most sensitive to L-M contrast modulations and least sensitive to L+M contrast modulations. Within V1, we observe little to no change in chromatic sensitivity as a function of eccentricity.https://elifesciences.org/articles/65590color visionfMRIV1isoresponse contourforward modelcontrast response function |
| spellingShingle | Michael A Barnett Geoffrey K Aguirre David Brainard A quadratic model captures the human V1 response to variations in chromatic direction and contrast eLife color vision fMRI V1 isoresponse contour forward model contrast response function |
| title | A quadratic model captures the human V1 response to variations in chromatic direction and contrast |
| title_full | A quadratic model captures the human V1 response to variations in chromatic direction and contrast |
| title_fullStr | A quadratic model captures the human V1 response to variations in chromatic direction and contrast |
| title_full_unstemmed | A quadratic model captures the human V1 response to variations in chromatic direction and contrast |
| title_short | A quadratic model captures the human V1 response to variations in chromatic direction and contrast |
| title_sort | quadratic model captures the human v1 response to variations in chromatic direction and contrast |
| topic | color vision fMRI V1 isoresponse contour forward model contrast response function |
| url | https://elifesciences.org/articles/65590 |
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