Spastic paraplegia as the predominant phenotype in a cohort of Chinese patients with adrenoleukodystrophy

Spastic paraplegia as the predominant phenotype in a cohort of Chinese patients with adrenoleukodystrophy

Abstract Background X‐linked adrenoleukodystrophy (ALD) is one of the most common peroxisomal disorders characterized by abnormal accumulation of very long‐chain fatty acids (VLCFA) in plasma and tissues and caused by mutations within ABCD1. Clinically, ALD present with various phenotypes, ranging f...

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Bibliographic Details
Main Authors: Wen‐Jiao Luo, Qiao Wei, Hai‐Lin Dong, Yang‐Tian Yan, Mei‐Jiao Chen, Hong‐Fu Li
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
ABCD1
hereditary spastic paraplegia
peroxisomal disease
very long‐chain fatty acids
X‐linked adrenoleukodystrophy
Online Access:https://doi.org/10.1002/mgg3.1065

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