Evaluation of MicroRNA-125b-5p and Transcription Factors BLIMP1 and IRF4 Expression in Unsolved Common Variable Immunodeficiency Patients

Evaluation of MicroRNA-125b-5p and Transcription Factors BLIMP1 and IRF4 Expression in Unsolved Common Variable Immunodeficiency Patients

Common variable immunodeficiency (CVID) is the most prevalent form of symptomatic primary humoral immunodeficiencies characterized by failure in the final differentiation of B lymphocytes. The majority of CVID cases have no identified genetic defect, and epigenetic alteration could be involved in th...

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Bibliographic Details
Main Authors: Zahra Hamidi Esfahani, Reza Yazdani, Sepideh Shahkarami, Fateme Babaha, Hassan Abolhassani, Maryam Sadr, Ali Akbar Pourfathollah, Asghar Aghamohammadi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2021-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Common Variable Immunodeficiency
Epigenesis
MicroRNAs
Primary immunodeficiency diseases;
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3172

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