Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease
A self-managed, home-based system for the automated assessment of a selected set of Parkinson’s disease motor symptoms is presented. The system makes use of an optical RGB-Depth device both to implement its gesture-based human computer interface and for the characterization and the evaluat...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-03-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/19/5/1129 |
| _version_ | 1811187264768704512 |
|---|---|
| author | Claudia Ferraris Roberto Nerino Antonio Chimienti Giuseppe Pettiti Nicola Cau Veronica Cimolin Corrado Azzaro Lorenzo Priano Alessandro Mauro |
| author_facet | Claudia Ferraris Roberto Nerino Antonio Chimienti Giuseppe Pettiti Nicola Cau Veronica Cimolin Corrado Azzaro Lorenzo Priano Alessandro Mauro |
| author_sort | Claudia Ferraris |
| collection | DOAJ |
| description | A self-managed, home-based system for the automated assessment of a selected set of Parkinson’s disease motor symptoms is presented. The system makes use of an optical RGB-Depth device both to implement its gesture-based human computer interface and for the characterization and the evaluation of posture and motor tasks, which are specified according to the Unified Parkinson’s Disease Rating Scale (UPDRS). Posture, lower limb movements and postural instability are characterized by kinematic parameters of the patient movement. During an experimental campaign, the performances of patients affected by Parkinson’s disease were simultaneously scored by neurologists and analyzed by the system. The sets of parameters which best correlated with the UPDRS scores of subjects’ performances were then used to train supervised classifiers for the automated assessment of new instances of the tasks. Results on the system usability and the assessment accuracy, as compared to clinical evaluations, indicate that the system is feasible for an objective and automated assessment of Parkinson’s disease at home, and it could be the basis for the development of neuromonitoring and neurorehabilitation applications in a telemedicine framework. |
| first_indexed | 2024-04-11T14:00:30Z |
| format | Article |
| id | doaj.art-6cfefe7ca8c74276a307744b8d8cad15 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T14:00:30Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-6cfefe7ca8c74276a307744b8d8cad152022-12-22T04:20:09ZengMDPI AGSensors1424-82202019-03-01195112910.3390/s19051129s19051129Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s DiseaseClaudia Ferraris0Roberto Nerino1Antonio Chimienti2Giuseppe Pettiti3Nicola Cau4Veronica Cimolin5Corrado Azzaro6Lorenzo Priano7Alessandro Mauro8Institute of Electronics, Computer and Telecommunication Engineering, National Research Council, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyInstitute of Electronics, Computer and Telecommunication Engineering, National Research Council, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyInstitute of Electronics, Computer and Telecommunication Engineering, National Research Council, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyInstitute of Electronics, Computer and Telecommunication Engineering, National Research Council, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyIstituto Auxologico Italiano, IRCCS, Department of Neurology and NeuroRehabilitation, S. Giuseppe Hospital, 28824 Piancavallo, Oggebbio (Verbania), ItalyDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, ItalyIstituto Auxologico Italiano, IRCCS, Department of Neurology and NeuroRehabilitation, S. Giuseppe Hospital, 28824 Piancavallo, Oggebbio (Verbania), ItalyIstituto Auxologico Italiano, IRCCS, Department of Neurology and NeuroRehabilitation, S. Giuseppe Hospital, 28824 Piancavallo, Oggebbio (Verbania), ItalyIstituto Auxologico Italiano, IRCCS, Department of Neurology and NeuroRehabilitation, S. Giuseppe Hospital, 28824 Piancavallo, Oggebbio (Verbania), ItalyA self-managed, home-based system for the automated assessment of a selected set of Parkinson’s disease motor symptoms is presented. The system makes use of an optical RGB-Depth device both to implement its gesture-based human computer interface and for the characterization and the evaluation of posture and motor tasks, which are specified according to the Unified Parkinson’s Disease Rating Scale (UPDRS). Posture, lower limb movements and postural instability are characterized by kinematic parameters of the patient movement. During an experimental campaign, the performances of patients affected by Parkinson’s disease were simultaneously scored by neurologists and analyzed by the system. The sets of parameters which best correlated with the UPDRS scores of subjects’ performances were then used to train supervised classifiers for the automated assessment of new instances of the tasks. Results on the system usability and the assessment accuracy, as compared to clinical evaluations, indicate that the system is feasible for an objective and automated assessment of Parkinson’s disease at home, and it could be the basis for the development of neuromonitoring and neurorehabilitation applications in a telemedicine framework.http://www.mdpi.com/1424-8220/19/5/1129Parkinson’s diseaseUPDRS tasksmovement disordersposturepostural stabilitycenter of massRGB-depthautomated assessmentmachine learningat-home monitoringneurorehabilitation |
| spellingShingle | Claudia Ferraris Roberto Nerino Antonio Chimienti Giuseppe Pettiti Nicola Cau Veronica Cimolin Corrado Azzaro Lorenzo Priano Alessandro Mauro Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease Sensors Parkinson’s disease UPDRS tasks movement disorders posture postural stability center of mass RGB-depth automated assessment machine learning at-home monitoring neurorehabilitation |
| title | Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease |
| title_full | Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease |
| title_fullStr | Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease |
| title_full_unstemmed | Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease |
| title_short | Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson’s Disease |
| title_sort | feasibility of home based automated assessment of postural instability and lower limb impairments in parkinson s disease |
| topic | Parkinson’s disease UPDRS tasks movement disorders posture postural stability center of mass RGB-depth automated assessment machine learning at-home monitoring neurorehabilitation |
| url | http://www.mdpi.com/1424-8220/19/5/1129 |
| work_keys_str_mv | AT claudiaferraris feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT robertonerino feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT antoniochimienti feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT giuseppepettiti feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT nicolacau feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT veronicacimolin feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT corradoazzaro feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT lorenzopriano feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease AT alessandromauro feasibilityofhomebasedautomatedassessmentofposturalinstabilityandlowerlimbimpairmentsinparkinsonsdisease |