Donepezil rescues spatial learning and memory deficits following traumatic brain injury independent of its effects on neurogenesis.

Donepezil rescues spatial learning and memory deficits following traumatic brain injury independent of its effects on neurogenesis.

Traumatic brain injury (TBI) is ubiquitous and effective treatments for it remain supportive largely due to uncertainty over how endogenous repair occurs. Recently, we demonstrated that hippocampal injury-induced neurogenesis is one mechanism underlying endogenous repair following TBI. Donepezil is...

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Bibliographic Details
Main Authors: Tzong-Shiue Yu, Ahleum Kim, Steven G Kernie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4340948?pdf=render

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