A review on the mechanisms underlying the antitumor effects of natural products by targeting the endoplasmic reticulum stress apoptosis pathway

A review on the mechanisms underlying the antitumor effects of natural products by targeting the endoplasmic reticulum stress apoptosis pathway

Cancer poses a substantial risk to human life and wellbeing as a result of its elevated incidence and fatality rates. Endoplasmic reticulum stress (ERS) is an important pathway that regulates cellular homeostasis. When ERS is under- or overexpressed, it activates the protein kinase R (PKR)-like endo...

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Bibliographic Details
Main Authors: Jie-Xiang Zhang, Wei-Chen Yuan, Cheng-Gang Li, Hai-Yan Zhang, Shu-Yan Han, Xiao-Hong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
endoplasmic reticulum stress
natural products
antitumor
apoptosis
review
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1293130/full

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