Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides
Despite the importance of unsymmetrical disulfides in various fields such as food chemistry, pharmaceutical industry, and polymer science, the nondirected intermolecular disulfuration of C-H bonds remains challenging. Here, the authors report the conversion of aliphatic C(sp3)-H bonds and aldehydic...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31617-5 |
| _version_ | 1811219157661777920 |
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| author | Jingjing Zhang Armido Studer |
| author_facet | Jingjing Zhang Armido Studer |
| author_sort | Jingjing Zhang |
| collection | DOAJ |
| description | Despite the importance of unsymmetrical disulfides in various fields such as food chemistry, pharmaceutical industry, and polymer science, the nondirected intermolecular disulfuration of C-H bonds remains challenging. Here, the authors report the conversion of aliphatic C(sp3)-H bonds and aldehydic C(sp2)-H bonds into the corresponding C-SS bonds with tetrasulfides (RSSSSR) as radical disulfuration reagents. |
| first_indexed | 2024-04-12T07:20:28Z |
| format | Article |
| id | doaj.art-6d0460fd6cc94379abd534762dfc6741 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T07:20:28Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-6d0460fd6cc94379abd534762dfc67412022-12-22T03:42:20ZengNature PortfolioNature Communications2041-17232022-07-011311810.1038/s41467-022-31617-5Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfidesJingjing Zhang0Armido Studer1Organisch-Chemisches Institut, Westfälische Wilhelms-UniversitätOrganisch-Chemisches Institut, Westfälische Wilhelms-UniversitätDespite the importance of unsymmetrical disulfides in various fields such as food chemistry, pharmaceutical industry, and polymer science, the nondirected intermolecular disulfuration of C-H bonds remains challenging. Here, the authors report the conversion of aliphatic C(sp3)-H bonds and aldehydic C(sp2)-H bonds into the corresponding C-SS bonds with tetrasulfides (RSSSSR) as radical disulfuration reagents.https://doi.org/10.1038/s41467-022-31617-5 |
| spellingShingle | Jingjing Zhang Armido Studer Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides Nature Communications |
| title | Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides |
| title_full | Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides |
| title_fullStr | Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides |
| title_full_unstemmed | Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides |
| title_short | Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides |
| title_sort | decatungstate catalyzed radical disulfuration through direct c h functionalization for the preparation of unsymmetrical disulfides |
| url | https://doi.org/10.1038/s41467-022-31617-5 |
| work_keys_str_mv | AT jingjingzhang decatungstatecatalyzedradicaldisulfurationthroughdirectchfunctionalizationforthepreparationofunsymmetricaldisulfides AT armidostuder decatungstatecatalyzedradicaldisulfurationthroughdirectchfunctionalizationforthepreparationofunsymmetricaldisulfides |