E90 subunit vaccine protects mice from Zika virus infection and microcephaly

E90 subunit vaccine protects mice from Zika virus infection and microcephaly

Abstract Zika virus (ZIKV) became a global threat due to its unprecedented outbreak and its association with congenital malformations such as microcephaly in developing fetuses and neonates. There are currently no effective vaccines or drugs available for the prevention or treatment of ZIKV infectio...

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Bibliographic Details
Main Authors: Xingliang Zhu, Chunfeng Li, Shabbir Khan Afridi, Shulong Zu, Jesse W. Xu, Natalie Quanquin, Heng Yang, Genhong Cheng, Zhiheng Xu
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Acta Neuropathologica Communications
Subjects:
Zika virus
E90 vaccine
Protection
Microcephaly
Mouse model
Online Access:http://link.springer.com/article/10.1186/s40478-018-0572-7

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