The promise of multi-omics approaches to discover biological alterations with clinical relevance in Alzheimer’s disease

The promise of multi-omics approaches to discover biological alterations with clinical relevance in Alzheimer’s disease

Beyond the core features of Alzheimer’s disease (AD) pathology, i.e. amyloid pathology, tau-related neurodegeneration and microglia response, multiple other molecular alterations and pathway dysregulations have been observed in AD. Their inter-individual variations, complex interactions and relevanc...

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Bibliographic Details
Main Authors: Christopher Clark, Miriam Rabl, Loïc Dayon, Julius Popp
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
multi-omics
Alzheimer’s disease
integration
clinical relevance
biomarkers
personalised medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1065904/full

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