Deep Learning-Based Automatic Detection of Ellipsoid Zone Loss in Spectral-Domain OCT for Hydroxychloroquine Retinal Toxicity Screening

Deep Learning-Based Automatic Detection of Ellipsoid Zone Loss in Spectral-Domain OCT for Hydroxychloroquine Retinal Toxicity Screening

Purpose: Retinal toxicity resulting from hydroxychloroquine use manifests photoreceptor loss and disruption of the ellipsoid zone (EZ) reflectivity band detectable on spectral-domain (SD) OCT imaging. This study investigated whether an automatic deep learning-based algorithm can detect and quantitat...

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Bibliographic Details
Main Authors: Tharindu De Silva, PhD, Gopal Jayakar, BS, Peyton Grisso, BS, Nathan Hotaling, PhD, Emily Y. Chew, MD, Catherine A. Cukras, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Ophthalmology Science
Subjects:
Automatic detection
Deep learning
Ellipsoid zone loss
Hydroxychloroquine toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914521000580

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