4-t-Butylbenzylation of carboxylic acid for GC–MS analysis
Abstract We report a 4-t-butylbenzyl derivatization for the analysis of carboxylic acids by GC–MS (EI). Carboxylic acids were analyzed as a 4-t-butylbenzyl ester after the derivatization with 4-t-butylbenzyl bromide. On the mass spectra of 4-t-butylbenzyl ester, [M-15]+ ions were observed with high...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2020-04-01
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| Series: | SN Applied Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s42452-020-2646-y |
| _version_ | 1818579903667240960 |
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| author | Shinji Tsunoi Nao Yamamoto Tomohiro Yasuhisa Riko Akehi Itaru Suzuki Ikuya Shibata |
| author_facet | Shinji Tsunoi Nao Yamamoto Tomohiro Yasuhisa Riko Akehi Itaru Suzuki Ikuya Shibata |
| author_sort | Shinji Tsunoi |
| collection | DOAJ |
| description | Abstract We report a 4-t-butylbenzyl derivatization for the analysis of carboxylic acids by GC–MS (EI). Carboxylic acids were analyzed as a 4-t-butylbenzyl ester after the derivatization with 4-t-butylbenzyl bromide. On the mass spectra of 4-t-butylbenzyl ester, [M-15]+ ions were observed with high intensity. These ions were tertiary benzyl cations generated by the elimination of a methyl radical from molecular ions. After optimization of the 4-t-butylbenzyl derivatization conditions using microwave reactor, we established a method for the determination of the carboxylic acids in water samples. The method showed good sensitivity and good reproducibility, and was successfully applied to the analysis of rain water samples. |
| first_indexed | 2024-12-16T07:09:06Z |
| format | Article |
| id | doaj.art-6d0a482ac13f43ce9bf4e49bae69bcdf |
| institution | Directory Open Access Journal |
| issn | 2523-3963 2523-3971 |
| language | English |
| last_indexed | 2024-12-16T07:09:06Z |
| publishDate | 2020-04-01 |
| publisher | Springer |
| record_format | Article |
| series | SN Applied Sciences |
| spelling | doaj.art-6d0a482ac13f43ce9bf4e49bae69bcdf2022-12-21T22:39:58ZengSpringerSN Applied Sciences2523-39632523-39712020-04-01251910.1007/s42452-020-2646-y4-t-Butylbenzylation of carboxylic acid for GC–MS analysisShinji Tsunoi0Nao Yamamoto1Tomohiro Yasuhisa2Riko Akehi3Itaru Suzuki4Ikuya Shibata5Research Center for Environmental Preservation, Osaka UniversityResearch Center for Environmental Preservation, Osaka UniversityResearch Center for Environmental Preservation, Osaka UniversityOsaka University SEEDS Program, Center for Education in Liberal Arts and Sciences, Osaka UniversityResearch Center for Environmental Preservation, Osaka UniversityResearch Center for Environmental Preservation, Osaka UniversityAbstract We report a 4-t-butylbenzyl derivatization for the analysis of carboxylic acids by GC–MS (EI). Carboxylic acids were analyzed as a 4-t-butylbenzyl ester after the derivatization with 4-t-butylbenzyl bromide. On the mass spectra of 4-t-butylbenzyl ester, [M-15]+ ions were observed with high intensity. These ions were tertiary benzyl cations generated by the elimination of a methyl radical from molecular ions. After optimization of the 4-t-butylbenzyl derivatization conditions using microwave reactor, we established a method for the determination of the carboxylic acids in water samples. The method showed good sensitivity and good reproducibility, and was successfully applied to the analysis of rain water samples.https://doi.org/10.1007/s42452-020-2646-yCarboxylic acidDerivatization4-t-butylbenzylationGC–MS analysisDetermination |
| spellingShingle | Shinji Tsunoi Nao Yamamoto Tomohiro Yasuhisa Riko Akehi Itaru Suzuki Ikuya Shibata 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis SN Applied Sciences Carboxylic acid Derivatization 4-t-butylbenzylation GC–MS analysis Determination |
| title | 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis |
| title_full | 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis |
| title_fullStr | 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis |
| title_full_unstemmed | 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis |
| title_short | 4-t-Butylbenzylation of carboxylic acid for GC–MS analysis |
| title_sort | 4 t butylbenzylation of carboxylic acid for gc ms analysis |
| topic | Carboxylic acid Derivatization 4-t-butylbenzylation GC–MS analysis Determination |
| url | https://doi.org/10.1007/s42452-020-2646-y |
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