Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial
Abstract Background Parathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of recovery of uremia patients with secondary hyperparathyroidism (SHPT) follo...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-09-01
|
| Series: | BMC Anesthesiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12871-021-01448-w |
| _version_ | 1818912387984523264 |
|---|---|
| author | Shenghong Hu Teng Shu Siqi Xu Xia Ju Shengbin Wang Li Ma |
| author_facet | Shenghong Hu Teng Shu Siqi Xu Xia Ju Shengbin Wang Li Ma |
| author_sort | Shenghong Hu |
| collection | DOAJ |
| description | Abstract Background Parathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of recovery of uremia patients with secondary hyperparathyroidism (SHPT) following parathyroidectomy. Methods Eighty-two uremia patients who underwent parathyroidectomy and exhibited SHPT were randomly allocated to the BSCPB group or the control group (CON group). The patients received ultrasound-guided BSCPB with 7.5 ml of ropivacaine 0.5% on each side (BSCPB group) or equal amount of 0.9% normal saline (CON group). The primary outcome of the Quality of Recovery-40(QoR-40) score was recorded on the day before surgery and postoperative day 1(POD1). Secondary outcomes including total consumption of remifentanil, time to first required rescue analgesia, number of patients requiring rescue analgesia, and total consumption of tramadol during the first 24 h after surgery were recorded. The occurrence of postoperative nausea or vomiting (PONV) and the visual analogue scale (VAS) scores were assessed and recorded. Results The scores on the pain and emotional state dimensions of the QoR-40 and the total QoR-40 score were higher in the BSCPB group than in the CON group on POD1 (P = 0.000). Compared with the CON group, the total consumption of remifentanil was significantly decreased in the BSCPB group (P = 0.000). The BSCPB group exhibited longer time to first required rescue analgesia (P = 0.018), fewer patients requiring rescue analgesia (P = 0.000), and lower postoperative total consumption of tramadol during the first 24 h after surgery (P = 0.000) than the CON group. The incidence of PONV was significantly lower in the BSCPB group than in the CON group (P = 0.013). The VAS scores in the BSCPB group were lower than those in the CON group at all time-points after surgery (P = 0.000). Conclusion Ultrasound-guided BSCPB with ropivacaine 0.5% can enhance the quality of recovery, postoperative analgesia, and reduce the incidence of PONV in uremia patients with SHPT following parathyroidectomy. Trial registration ChiCTR1900027185 . (Prospective registered). Initial registration date was 04/11/2019. |
| first_indexed | 2024-12-19T23:13:48Z |
| format | Article |
| id | doaj.art-6d0aa40cda204f17906a4dc0198dd0a0 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-12-19T23:13:48Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-6d0aa40cda204f17906a4dc0198dd0a02022-12-21T20:02:09ZengBMCBMC Anesthesiology1471-22532021-09-012111910.1186/s12871-021-01448-wUltrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trialShenghong Hu0Teng Shu1Siqi Xu2Xia Ju3Shengbin Wang4Li Ma5Department of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical UniversityDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical UniversityDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical UniversityDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical UniversityDepartment of Anesthesiology, Anqing Hospital Affiliated with Anhui Medical UniversityDepartment of Thyroid and Breast Surgery, Anqing Hospital Affiliated with Anhui Medical UniversityAbstract Background Parathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of recovery of uremia patients with secondary hyperparathyroidism (SHPT) following parathyroidectomy. Methods Eighty-two uremia patients who underwent parathyroidectomy and exhibited SHPT were randomly allocated to the BSCPB group or the control group (CON group). The patients received ultrasound-guided BSCPB with 7.5 ml of ropivacaine 0.5% on each side (BSCPB group) or equal amount of 0.9% normal saline (CON group). The primary outcome of the Quality of Recovery-40(QoR-40) score was recorded on the day before surgery and postoperative day 1(POD1). Secondary outcomes including total consumption of remifentanil, time to first required rescue analgesia, number of patients requiring rescue analgesia, and total consumption of tramadol during the first 24 h after surgery were recorded. The occurrence of postoperative nausea or vomiting (PONV) and the visual analogue scale (VAS) scores were assessed and recorded. Results The scores on the pain and emotional state dimensions of the QoR-40 and the total QoR-40 score were higher in the BSCPB group than in the CON group on POD1 (P = 0.000). Compared with the CON group, the total consumption of remifentanil was significantly decreased in the BSCPB group (P = 0.000). The BSCPB group exhibited longer time to first required rescue analgesia (P = 0.018), fewer patients requiring rescue analgesia (P = 0.000), and lower postoperative total consumption of tramadol during the first 24 h after surgery (P = 0.000) than the CON group. The incidence of PONV was significantly lower in the BSCPB group than in the CON group (P = 0.013). The VAS scores in the BSCPB group were lower than those in the CON group at all time-points after surgery (P = 0.000). Conclusion Ultrasound-guided BSCPB with ropivacaine 0.5% can enhance the quality of recovery, postoperative analgesia, and reduce the incidence of PONV in uremia patients with SHPT following parathyroidectomy. Trial registration ChiCTR1900027185 . (Prospective registered). Initial registration date was 04/11/2019.https://doi.org/10.1186/s12871-021-01448-wUltrasound-guidedSuperficial cervical plexus blockQuality of recoveryUremiaSecondary hyperparathyroidismParathyroidectomy |
| spellingShingle | Shenghong Hu Teng Shu Siqi Xu Xia Ju Shengbin Wang Li Ma Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial BMC Anesthesiology Ultrasound-guided Superficial cervical plexus block Quality of recovery Uremia Secondary hyperparathyroidism Parathyroidectomy |
| title | Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial |
| title_full | Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial |
| title_fullStr | Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial |
| title_full_unstemmed | Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial |
| title_short | Ultrasound-guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy: a randomized controlled trial |
| title_sort | ultrasound guided bilateral superficial cervical plexus block enhances the quality of recovery of uremia patients with secondary hyperparathyroidism following parathyroidectomy a randomized controlled trial |
| topic | Ultrasound-guided Superficial cervical plexus block Quality of recovery Uremia Secondary hyperparathyroidism Parathyroidectomy |
| url | https://doi.org/10.1186/s12871-021-01448-w |
| work_keys_str_mv | AT shenghonghu ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial AT tengshu ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial AT siqixu ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial AT xiaju ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial AT shengbinwang ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial AT lima ultrasoundguidedbilateralsuperficialcervicalplexusblockenhancesthequalityofrecoveryofuremiapatientswithsecondaryhyperparathyroidismfollowingparathyroidectomyarandomizedcontrolledtrial |