Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18)
<p>Abstract</p> <p>Background</p> <p>This study examined the measurement properties of the Japanese version of the European Organisation for Research and Treatment of Cancer (EORTC) Hepatocellular Carcinoma-Specific Quality of Life Questionnaire (QLQ-HCC18).</p> &...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-05-01
|
Series: | Health and Quality of Life Outcomes |
Subjects: | |
Online Access: | http://www.hqlo.com/content/10/1/58 |
_version_ | 1811259906350645248 |
---|---|
author | Mikoshiba Naoko Tateishi Ryosuke Tanaka Makoto Sakai Tomoko Blazeby Jane M Kokudo Norihiro Koike Kazuhiko Kazuma Keiko |
author_facet | Mikoshiba Naoko Tateishi Ryosuke Tanaka Makoto Sakai Tomoko Blazeby Jane M Kokudo Norihiro Koike Kazuhiko Kazuma Keiko |
author_sort | Mikoshiba Naoko |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>This study examined the measurement properties of the Japanese version of the European Organisation for Research and Treatment of Cancer (EORTC) Hepatocellular Carcinoma-Specific Quality of Life Questionnaire (QLQ-HCC18).</p> <p>Methods</p> <p>EORTC quality of life (QOL) translation guidelines were followed to create a Japanese version of the EORTC QLQ-HCC18. This was then administered to 192 patients with hepatocellular carcinoma along with the EORTC QLQ-C30 and FACT-Hep questionnaires. Tests for reliability and validity were conducted including comparison of scores between the EORTC and FACT questionnaire and detailed assessment of the new scales and items in clinically distinct groups of patients.</p> <p>Results</p> <p>Multi-trait scaling analysis confirmed three putative scales in the QLQ-HCC18, fatigue, fever and nutrition. Cronbach’s alpha for these scales were between 0.68 and 0.78. The QLQ-HCC18 scales correlated with scales measuring similar items in the FACT-Hep and the questionnaire was stable over time with an intra-class correlation score of 0.70 for almost all scales. The questionnaire had the ability to distinguish between patients with different Karnofsky Performance Status, and Child-Pugh liver function class.</p> <p>Conclusions</p> <p>The Japanese version of EORTC QLQ-HCC18 is a reliable supplementary measure to use with EORTC QLQ-C30 to measure QOL in Japanese patients with hepatocellular carcinoma.</p> |
first_indexed | 2024-04-12T18:39:42Z |
format | Article |
id | doaj.art-6d0f7b48aa5d43e088b291862e5af1c7 |
institution | Directory Open Access Journal |
issn | 1477-7525 |
language | English |
last_indexed | 2024-04-12T18:39:42Z |
publishDate | 2012-05-01 |
publisher | BMC |
record_format | Article |
series | Health and Quality of Life Outcomes |
spelling | doaj.art-6d0f7b48aa5d43e088b291862e5af1c72022-12-22T03:20:50ZengBMCHealth and Quality of Life Outcomes1477-75252012-05-011015810.1186/1477-7525-10-58Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18)Mikoshiba NaokoTateishi RyosukeTanaka MakotoSakai TomokoBlazeby Jane MKokudo NorihiroKoike KazuhikoKazuma Keiko<p>Abstract</p> <p>Background</p> <p>This study examined the measurement properties of the Japanese version of the European Organisation for Research and Treatment of Cancer (EORTC) Hepatocellular Carcinoma-Specific Quality of Life Questionnaire (QLQ-HCC18).</p> <p>Methods</p> <p>EORTC quality of life (QOL) translation guidelines were followed to create a Japanese version of the EORTC QLQ-HCC18. This was then administered to 192 patients with hepatocellular carcinoma along with the EORTC QLQ-C30 and FACT-Hep questionnaires. Tests for reliability and validity were conducted including comparison of scores between the EORTC and FACT questionnaire and detailed assessment of the new scales and items in clinically distinct groups of patients.</p> <p>Results</p> <p>Multi-trait scaling analysis confirmed three putative scales in the QLQ-HCC18, fatigue, fever and nutrition. Cronbach’s alpha for these scales were between 0.68 and 0.78. The QLQ-HCC18 scales correlated with scales measuring similar items in the FACT-Hep and the questionnaire was stable over time with an intra-class correlation score of 0.70 for almost all scales. The questionnaire had the ability to distinguish between patients with different Karnofsky Performance Status, and Child-Pugh liver function class.</p> <p>Conclusions</p> <p>The Japanese version of EORTC QLQ-HCC18 is a reliable supplementary measure to use with EORTC QLQ-C30 to measure QOL in Japanese patients with hepatocellular carcinoma.</p>http://www.hqlo.com/content/10/1/58EORTC QLQ-HCC18FACT-HepHepatocellular carcinomaQuality of lifeQuestionnaire |
spellingShingle | Mikoshiba Naoko Tateishi Ryosuke Tanaka Makoto Sakai Tomoko Blazeby Jane M Kokudo Norihiro Koike Kazuhiko Kazuma Keiko Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) Health and Quality of Life Outcomes EORTC QLQ-HCC18 FACT-Hep Hepatocellular carcinoma Quality of life Questionnaire |
title | Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) |
title_full | Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) |
title_fullStr | Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) |
title_full_unstemmed | Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) |
title_short | Validation of the Japanese version of the EORTC hepatocellular carcinoma-specific quality of life questionnaire module (QLQ-HCC18) |
title_sort | validation of the japanese version of the eortc hepatocellular carcinoma specific quality of life questionnaire module qlq hcc18 |
topic | EORTC QLQ-HCC18 FACT-Hep Hepatocellular carcinoma Quality of life Questionnaire |
url | http://www.hqlo.com/content/10/1/58 |
work_keys_str_mv | AT mikoshibanaoko validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT tateishiryosuke validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT tanakamakoto validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT sakaitomoko validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT blazebyjanem validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT kokudonorihiro validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT koikekazuhiko validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 AT kazumakeiko validationofthejapaneseversionoftheeortchepatocellularcarcinomaspecificqualityoflifequestionnairemoduleqlqhcc18 |