Identification of Two Subsets of Subcompartment A1 Associated with High Transcriptional Activity and Frequent Loop Extrusion

Identification of Two Subsets of Subcompartment A1 Associated with High Transcriptional Activity and Frequent Loop Extrusion

Three-dimensional genome organization has been increasingly recognized as an important determinant of the precise regulation of gene expression in mammalian cells, yet the relationship between gene transcriptional activity and spatial subcompartment positioning is still not fully comprehended. Here,...

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Bibliographic Details
Main Authors: Zihang Yin, Shuang Cui, Song Xue, Yufan Xie, Yefan Wang, Chengling Zhao, Zhiyu Zhang, Tao Wu, Guojun Hou, Wuming Wang, Sheila Q. Xie, Yue Wu, Ya Guo
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
genome folding
A/B compartments
TADs
contact domains
chromatin looping
tissue-specific gene
Online Access:https://www.mdpi.com/2079-7737/12/8/1058

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