Constructing perfect phylogenies and proper triangulations for three-state characters

<p>Abstract</p> <p/> <p>In this paper, we study the problem of constructing perfect phylogenies for three-state characters. Our work builds on two recent results. The first result states that for three-state characters, the local condition of examining all subsets of three ch...

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Main Authors: Gysel Rob, Lam Fumei, Gusfield Dan
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:http://www.almob.org/content/7/1/26
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author Gysel Rob
Lam Fumei
Gusfield Dan
author_facet Gysel Rob
Lam Fumei
Gusfield Dan
author_sort Gysel Rob
collection DOAJ
description <p>Abstract</p> <p/> <p>In this paper, we study the problem of constructing perfect phylogenies for three-state characters. Our work builds on two recent results. The first result states that for three-state characters, the local condition of examining all subsets of three characters is sufficient to determine the global property of admitting a perfect phylogeny. The second result applies tools from minimal triangulation theory to the partition intersection graph to determine if a perfect phylogeny exists. Despite the wealth of combinatorial tools and algorithms stemming from the chordal graph and minimal triangulation literature, it is unclear how to use such approaches to efficiently construct a perfect phylogeny for three-state characters when the data admits one. We utilize structural properties of both the partition intersection graph and the original data in order to achieve a competitive time bound.</p>
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spelling doaj.art-6d12b49e376941dfbb93feab20e931b12022-12-22T03:05:28ZengBMCAlgorithms for Molecular Biology1748-71882012-09-01712610.1186/1748-7188-7-26Constructing perfect phylogenies and proper triangulations for three-state charactersGysel RobLam FumeiGusfield Dan<p>Abstract</p> <p/> <p>In this paper, we study the problem of constructing perfect phylogenies for three-state characters. Our work builds on two recent results. The first result states that for three-state characters, the local condition of examining all subsets of three characters is sufficient to determine the global property of admitting a perfect phylogeny. The second result applies tools from minimal triangulation theory to the partition intersection graph to determine if a perfect phylogeny exists. Despite the wealth of combinatorial tools and algorithms stemming from the chordal graph and minimal triangulation literature, it is unclear how to use such approaches to efficiently construct a perfect phylogeny for three-state characters when the data admits one. We utilize structural properties of both the partition intersection graph and the original data in order to achieve a competitive time bound.</p>http://www.almob.org/content/7/1/26Perfect phylogenyChordal graphMinimal triangulationMinimal separator
spellingShingle Gysel Rob
Lam Fumei
Gusfield Dan
Constructing perfect phylogenies and proper triangulations for three-state characters
Algorithms for Molecular Biology
Perfect phylogeny
Chordal graph
Minimal triangulation
Minimal separator
title Constructing perfect phylogenies and proper triangulations for three-state characters
title_full Constructing perfect phylogenies and proper triangulations for three-state characters
title_fullStr Constructing perfect phylogenies and proper triangulations for three-state characters
title_full_unstemmed Constructing perfect phylogenies and proper triangulations for three-state characters
title_short Constructing perfect phylogenies and proper triangulations for three-state characters
title_sort constructing perfect phylogenies and proper triangulations for three state characters
topic Perfect phylogeny
Chordal graph
Minimal triangulation
Minimal separator
url http://www.almob.org/content/7/1/26
work_keys_str_mv AT gyselrob constructingperfectphylogeniesandpropertriangulationsforthreestatecharacters
AT lamfumei constructingperfectphylogeniesandpropertriangulationsforthreestatecharacters
AT gusfielddan constructingperfectphylogeniesandpropertriangulationsforthreestatecharacters