Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment

Peripheral neuropathies constitute a group of disorders affecting the peripheral nervous system. Neuropathies have multiple causes such as infections (i.e., COVID-19), diabetes, and nutritional (low vitamin levels), among others. Many micronutrients, such as vitamins (A, C, D, E, B6, B12, and folate...

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Main Authors: Alfredo Córdova-Martínez, Alberto Caballero-García, Daniel Pérez-Valdecantos, Enrique Roche, David César Noriega-González
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/5/1051
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author Alfredo Córdova-Martínez
Alberto Caballero-García
Daniel Pérez-Valdecantos
Enrique Roche
David César Noriega-González
author_facet Alfredo Córdova-Martínez
Alberto Caballero-García
Daniel Pérez-Valdecantos
Enrique Roche
David César Noriega-González
author_sort Alfredo Córdova-Martínez
collection DOAJ
description Peripheral neuropathies constitute a group of disorders affecting the peripheral nervous system. Neuropathies have multiple causes such as infections (i.e., COVID-19), diabetes, and nutritional (low vitamin levels), among others. Many micronutrients, such as vitamins (A, C, D, E, B6, B12, and folate), certain minerals (Fe, Mg, Zn, Se, and Cu), and ω-3 fatty acids have immunomodulatory effects. Therefore, they may play an instrumental role in the treatment of COVID-19 infection. However, many COVID-19 patients can undergo neuropathy. In this context, there is a wealth of information on a variety of first-, second-, and third-line treatment options. This review focuses on the application of nutraceutical strategies in order to improve the symptomatology of neuropathy and neuropathic pain in patients that suffered from COVID-19. Our aim is to provide an alternative vision to traditional medical-pharmacological treatment through nutraceuticals.
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spelling doaj.art-6d15b6d8150b45fa8f7c496bf7f898402023-11-23T10:10:19ZengMDPI AGBiomedicines2227-90592022-05-01105105110.3390/biomedicines10051051Peripheral Neuropathies Derived from COVID-19: New Perspectives for TreatmentAlfredo Córdova-Martínez0Alberto Caballero-García1Daniel Pérez-Valdecantos2Enrique Roche3David César Noriega-González4Department of Biochemistry, Molecular Biology and Physiology, Faculty of Health Sciences, GIR Physical Exercise and Aging, University of Valladolid, Campus Duques de Soria, 42004 Soria, SpainDepartment of Anatomy and Radiology, Faculty of Health Sciences, GIR Physical Exercise and Aging, University of Valladolid, Campus Duques de Soria, 42004 Soria, SpainDepartment of Biochemistry, Molecular Biology and Physiology, Faculty of Health Sciences, GIR Physical Exercise and Aging, University of Valladolid, Campus Duques de Soria, 42004 Soria, SpainDepartment of Applied Biology-Nutrition, Institute of Bioengineering, University Miguel Hernández, 03202 Elche, SpainDepartment of Surgery, Ophthalmology, Otorhinolaryngology and Physiotherapy, Faculty of Medicine, Hospital Clínico Universitario de Valladolid, 47005 Valladolid, SpainPeripheral neuropathies constitute a group of disorders affecting the peripheral nervous system. Neuropathies have multiple causes such as infections (i.e., COVID-19), diabetes, and nutritional (low vitamin levels), among others. Many micronutrients, such as vitamins (A, C, D, E, B6, B12, and folate), certain minerals (Fe, Mg, Zn, Se, and Cu), and ω-3 fatty acids have immunomodulatory effects. Therefore, they may play an instrumental role in the treatment of COVID-19 infection. However, many COVID-19 patients can undergo neuropathy. In this context, there is a wealth of information on a variety of first-, second-, and third-line treatment options. This review focuses on the application of nutraceutical strategies in order to improve the symptomatology of neuropathy and neuropathic pain in patients that suffered from COVID-19. Our aim is to provide an alternative vision to traditional medical-pharmacological treatment through nutraceuticals.https://www.mdpi.com/2227-9059/10/5/1051α-lipoic acidCOVID-19nutraceuticalsperipheral neuropathyvitamins
spellingShingle Alfredo Córdova-Martínez
Alberto Caballero-García
Daniel Pérez-Valdecantos
Enrique Roche
David César Noriega-González
Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
Biomedicines
α-lipoic acid
COVID-19
nutraceuticals
peripheral neuropathy
vitamins
title Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
title_full Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
title_fullStr Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
title_full_unstemmed Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
title_short Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment
title_sort peripheral neuropathies derived from covid 19 new perspectives for treatment
topic α-lipoic acid
COVID-19
nutraceuticals
peripheral neuropathy
vitamins
url https://www.mdpi.com/2227-9059/10/5/1051
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