Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study
Background and aims: Gestational diabetes has long-term adverse consequences for both the mother and child and seems to be a risk factor for attention deficit hyperactivity disorder (ADHD) in children. However, no research has been conducted in this regard in Iran. Methods: This was a case-control s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Shahrekord University of Medical Sciences
2023-01-01
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| Series: | Journal of Shahrekord University of Medical Sciences |
| Subjects: | |
| Online Access: | https://j.skums.ac.ir/PDF/jskums-25-23.pdf |
| _version_ | 1797851716305027072 |
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| author | Soleiman Mohammadzadeh Samad Hamidi Mohammad Aziz Rasouli Bahar Sahadatmand Bushra Zareie |
| author_facet | Soleiman Mohammadzadeh Samad Hamidi Mohammad Aziz Rasouli Bahar Sahadatmand Bushra Zareie |
| author_sort | Soleiman Mohammadzadeh |
| collection | DOAJ |
| description | Background and aims: Gestational diabetes has long-term adverse consequences for both the mother and child and seems to be a risk factor for attention deficit hyperactivity disorder (ADHD) in children. However, no research has been conducted in this regard in Iran. Methods: This was a case-control study. The sample consisted of 225 children who were referred to the general and psychiatric clinic of Besat Hospital in Sanandaj and were evaluated for a history of maternal diabetes in the fetal period. The diagnosis of ADHD in children was based on a structured clinical interview with Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) by a psychiatrist and a short and revised form of Conners’ parent scale. The data were analyzed using Stata 14. Results: The results showed that 25.3% of the mothers of children with ADHD had gestational diabetes during pregnancy, and 17.3% were taking diabetes medication. However, the results revealed that there is no statistically significant relationship between the history of gestational diabetes and ADHD (P=0.427). Furthermore, the logistic regression results demonstrated that the place of residence (P<0.027, OR=8.351) increases the probability of suffering from ADHD in children, while the age of the mother during pregnancy (P<0.031, OR=0.907) decreases the probability of the child suffering from ADHD. Conclusion: Although cohort studies have associated gestational diabetes with an increased risk of ADHD in children, the results of this case-control study do not support this association. |
| first_indexed | 2024-04-09T19:21:11Z |
| format | Article |
| id | doaj.art-6d16c17c3fb4422abd00a262c9925382 |
| institution | Directory Open Access Journal |
| issn | 2717-0071 |
| language | English |
| last_indexed | 2024-04-09T19:21:11Z |
| publishDate | 2023-01-01 |
| publisher | Shahrekord University of Medical Sciences |
| record_format | Article |
| series | Journal of Shahrekord University of Medical Sciences |
| spelling | doaj.art-6d16c17c3fb4422abd00a262c99253822023-04-05T10:04:41ZengShahrekord University of Medical SciencesJournal of Shahrekord University of Medical Sciences2717-00712023-01-01251232910.34172/jsums.2023.724jskums-724Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control studySoleiman Mohammadzadeh0Samad Hamidi1Mohammad Aziz Rasouli2Bahar Sahadatmand3Bushra Zareie4Child and Adolescent Psychiatrist, Neurosciences Research Center, Kurdistan University of Medical Sciences, Sanandaj, IranClinical Psychologist, Afra Consulting Center, Sanandaj, IranMSc Epidemiology, Clinical Research Development Unit, Kowsar Hospital, Kurdistan University of Medical Sciences, Sanandaj, IranMedical Doctor, Department of Emergency Medicine, Kurdistan University of Medical Sciences, Sanandaj, IranHealth Data Processing Research Center, Kurdistan University of Medical Sciences, Sanandaj, IranBackground and aims: Gestational diabetes has long-term adverse consequences for both the mother and child and seems to be a risk factor for attention deficit hyperactivity disorder (ADHD) in children. However, no research has been conducted in this regard in Iran. Methods: This was a case-control study. The sample consisted of 225 children who were referred to the general and psychiatric clinic of Besat Hospital in Sanandaj and were evaluated for a history of maternal diabetes in the fetal period. The diagnosis of ADHD in children was based on a structured clinical interview with Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) by a psychiatrist and a short and revised form of Conners’ parent scale. The data were analyzed using Stata 14. Results: The results showed that 25.3% of the mothers of children with ADHD had gestational diabetes during pregnancy, and 17.3% were taking diabetes medication. However, the results revealed that there is no statistically significant relationship between the history of gestational diabetes and ADHD (P=0.427). Furthermore, the logistic regression results demonstrated that the place of residence (P<0.027, OR=8.351) increases the probability of suffering from ADHD in children, while the age of the mother during pregnancy (P<0.031, OR=0.907) decreases the probability of the child suffering from ADHD. Conclusion: Although cohort studies have associated gestational diabetes with an increased risk of ADHD in children, the results of this case-control study do not support this association.https://j.skums.ac.ir/PDF/jskums-25-23.pdfgestational diabetesattention deficit hyperactivity disorderadhdmaternal diabetes |
| spellingShingle | Soleiman Mohammadzadeh Samad Hamidi Mohammad Aziz Rasouli Bahar Sahadatmand Bushra Zareie Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study Journal of Shahrekord University of Medical Sciences gestational diabetes attention deficit hyperactivity disorder adhd maternal diabetes |
| title | Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study |
| title_full | Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study |
| title_fullStr | Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study |
| title_full_unstemmed | Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study |
| title_short | Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study |
| title_sort | association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an iranian population a case control study |
| topic | gestational diabetes attention deficit hyperactivity disorder adhd maternal diabetes |
| url | https://j.skums.ac.ir/PDF/jskums-25-23.pdf |
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