The HIF-1α as a Potent Inducer of the Hallmarks in Gastric Cancer

The HIF-1α as a Potent Inducer of the Hallmarks in Gastric Cancer

Hypoxia is the principal architect of the topographic heterogeneity in tumors. Hypoxia-inducible factor-1α (HIF-1α) reinforces all hallmarks of cancer and donates cancer cells with more aggressive characteristics at hypoxic niches. HIF-1α potently induces sustained growth factor signaling, angiogene...

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Bibliographic Details
Main Authors:	Cemre Ucaryilmaz Metin, Gulnihal Ozcan
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Series:	Cancers
Subjects:	gastric cancer hypoxia hypoxia-inducible factor-1α hallmarks of cancer
Online Access:	https://www.mdpi.com/2072-6694/14/11/2711

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