Role of Premycofactocin Synthase in Growth, Microaerophilic Adaptation, and Metabolism of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Role of Premycofactocin Synthase in Growth, Microaerophilic Adaptation, and Metabolism of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Mycofactocin is a new class of peptide-derived redox cofactors present in a selected group of bacteria including Mycobacterium tuberculosis. Mycofactocin biosynthesis requires at least six genes, including mftD, encoding putative lactate dehydrogenase, which catalyzes the penultimate biosyn...

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Bibliographic Details
Main Authors: Gopinath Krishnamoorthy, Peggy Kaiser, Patricia Constant, Ulrike Abu Abed, Monika Schmid, Christian K. Frese, Volker Brinkmann, Mamadou Daffé, Stefan H. E. Kaufmann
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
mycofactocin
hypoxia
redox cofactor
glucose metabolism
protein aggregation
Mycobacterium tuberculosis
Online Access:https://journals.asm.org/doi/10.1128/mBio.01665-21

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