Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties
Over the past two decades, several advances have been made in the management of patients with inflammatory bowel disease (IBD) from both evaluative and therapeutic perspectives. This review discusses the medical advancements that have recently been made as the standard of care for managing patients...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | The Saudi Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2014;volume=20;issue=2;spage=81;epage=101;aulast=Mosli |
| _version_ | 1828332983857184768 |
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| author | Mahmoud Mosli Mohammad Al Beshir Bandar Al-Judaibi Turki Al-Ameel Abdulaziz Saleem Talat Bessissow Subrata Ghosh Majid Almadi |
| author_facet | Mahmoud Mosli Mohammad Al Beshir Bandar Al-Judaibi Turki Al-Ameel Abdulaziz Saleem Talat Bessissow Subrata Ghosh Majid Almadi |
| author_sort | Mahmoud Mosli |
| collection | DOAJ |
| description | Over the past two decades, several advances have been made in the management of patients with inflammatory bowel disease (IBD) from both evaluative and therapeutic perspectives. This review discusses the medical advancements that have recently been made as the standard of care for managing patients with ulcerative colitis (UC) and Crohn′s Disease (CD) and to identify the challenges associated with implementing their use in clinical practice. A comprehensive literature search of the major databases (PubMed and Embase) was conducted for all recent scientific papers (1990-2013) giving the recent updates on the management of IBD and the data were extracted. The reported advancements in managing IBD range from diagnostic and evaluative tools, such as genetic tests, biochemical surrogate markers of activity, endoscopic techniques, and radiological modalities, to therapeutic advances, which encompass medical, endoscopic, and surgical interventions. There are limited studies addressing the cost-effectiveness and the impact that these advances have had on medical practice. The majority of the advances developed for managing IBD, while considered instrumental by some IBD experts in improving patient care, have questionable applications due to constraints of cost, lack of availability, and most importantly, insufficient evidence that supports their role in improving important long-term health-related outcomes. |
| first_indexed | 2024-04-13T21:13:20Z |
| format | Article |
| id | doaj.art-6d1c91d3fe474547bbc04cacaaa715c7 |
| institution | Directory Open Access Journal |
| issn | 1319-3767 1998-4049 |
| language | English |
| last_indexed | 2024-04-13T21:13:20Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Saudi Journal of Gastroenterology |
| spelling | doaj.art-6d1c91d3fe474547bbc04cacaaa715c72022-12-22T02:29:46ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492014-01-012028110110.4103/1319-3767.129473Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertaintiesMahmoud MosliMohammad Al BeshirBandar Al-JudaibiTurki Al-AmeelAbdulaziz SaleemTalat BessissowSubrata GhoshMajid AlmadiOver the past two decades, several advances have been made in the management of patients with inflammatory bowel disease (IBD) from both evaluative and therapeutic perspectives. This review discusses the medical advancements that have recently been made as the standard of care for managing patients with ulcerative colitis (UC) and Crohn′s Disease (CD) and to identify the challenges associated with implementing their use in clinical practice. A comprehensive literature search of the major databases (PubMed and Embase) was conducted for all recent scientific papers (1990-2013) giving the recent updates on the management of IBD and the data were extracted. The reported advancements in managing IBD range from diagnostic and evaluative tools, such as genetic tests, biochemical surrogate markers of activity, endoscopic techniques, and radiological modalities, to therapeutic advances, which encompass medical, endoscopic, and surgical interventions. There are limited studies addressing the cost-effectiveness and the impact that these advances have had on medical practice. The majority of the advances developed for managing IBD, while considered instrumental by some IBD experts in improving patient care, have questionable applications due to constraints of cost, lack of availability, and most importantly, insufficient evidence that supports their role in improving important long-term health-related outcomes.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2014;volume=20;issue=2;spage=81;epage=101;aulast=MosliAdvancementsCrohn′s diseasediagnosismanagementreviewtreatmentupdateulcerative colitis |
| spellingShingle | Mahmoud Mosli Mohammad Al Beshir Bandar Al-Judaibi Turki Al-Ameel Abdulaziz Saleem Talat Bessissow Subrata Ghosh Majid Almadi Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties The Saudi Journal of Gastroenterology Advancements Crohn′s disease diagnosis management review treatment update ulcerative colitis |
| title | Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties |
| title_full | Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties |
| title_fullStr | Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties |
| title_full_unstemmed | Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties |
| title_short | Advances in the diagnosis and management of inflammatory bowel disease: Challenges and uncertainties |
| title_sort | advances in the diagnosis and management of inflammatory bowel disease challenges and uncertainties |
| topic | Advancements Crohn′s disease diagnosis management review treatment update ulcerative colitis |
| url | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2014;volume=20;issue=2;spage=81;epage=101;aulast=Mosli |
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