Integrative analysis reveals associations between oral microbiota dysbiosis and host genetic and epigenetic aberrations in oral cavity squamous cell carcinoma

Abstract Dysbiosis of the human oral microbiota has been reported to be associated with oral cavity squamous cell carcinoma (OSCC) while the host-microbiota interactions with respect to the potential impact of pathogenic bacteria on host genomic and epigenomic abnormalities remain poorly studied. In...

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Bibliographic Details
Main Authors: Liuyang Cai, Hengyan Zhu, Qianqian Mou, Po Yee Wong, Linlin Lan, Cherrie W. K. Ng, Pu Lei, Man Kit Cheung, Daijuanru Wang, Eddy W. Y. Wong, Eric H. L. Lau, Zenon W. C. Yeung, Ronald Lai, Katie Meehan, Sherwood Fung, Kwan Chee A. Chan, Vivian W. Y. Lui, Alfred S. L. Cheng, Jun Yu, Paul K. S. Chan, Jason Y. K. Chan, Zigui Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-024-00511-x