Polar protein Wag31 both activates and inhibits cell wall metabolism at the poles and septum

Polar protein Wag31 both activates and inhibits cell wall metabolism at the poles and septum

Mycobacterial cell elongation occurs at the cell poles; however, it is not clear how cell wall insertion is restricted to the pole or how it is organized. Wag31 is a pole-localized cytoplasmic protein that is essential for polar growth, but its molecular function has not been described. In this stud...

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Bibliographic Details
Main Authors: Neda Habibi Arejan, Delfina Ensinck, Lautaro Diacovich, Parthvi Bharatkumar Patel, Samantha Y. Quintanilla, Arash Emami Saleh, Hugo Gramajo, Cara C. Boutte
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium
polar growth regulation
petidoglycan synthesis
DivIVA, intracellular membrane domain (IMD)
MurG
ACCase complex
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1085918/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1085918/full

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