Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient
Drug-coated balloons (DCB) are a treatment alternative to conventional angioplasty in arterial, hemodialysis fistulas, and venous stenoses. This case report describes a child with the diagnosis of hepatoblastoma treated with chemotherapy and a right extended hepatectomy with venous reconstruction. T...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-10-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320303551 |
| _version_ | 1818409596878848000 |
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| author | Dimitri A. Parra, MD Leonardo Brandao, MD |
| author_facet | Dimitri A. Parra, MD Leonardo Brandao, MD |
| author_sort | Dimitri A. Parra, MD |
| collection | DOAJ |
| description | Drug-coated balloons (DCB) are a treatment alternative to conventional angioplasty in arterial, hemodialysis fistulas, and venous stenoses. This case report describes a child with the diagnosis of hepatoblastoma treated with chemotherapy and a right extended hepatectomy with venous reconstruction. The patient presented with signs and symptoms of portal hypertension due to a hepatic venous outflow obstruction secondary to stenosis of the surgical anastomosis. The response to conventional angioplasty was limited with frequent recurrence of symptoms. DCBs were used as an alternative prior to stent consideration aiming to assess if these devices could provide improvement of the symptoms and as a long-term therapy. The use of DCBs increased the time interval of reinterventions in comparison with conventional angioplasty. The patient eventually required stents due to recurrence of the primary disease.While this report does not provide an in-depth evaluation in terms of the efficacy and safety of DCB, this case illustrates a potential novel treatment modality to be considered for children, when stenotic venous lesions not amenable for stenting are present. |
| first_indexed | 2024-12-14T10:02:09Z |
| format | Article |
| id | doaj.art-6d1ef0530bfa4bfaa9cfe16befd1d069 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-14T10:02:09Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-6d1ef0530bfa4bfaa9cfe16befd1d0692022-12-21T23:07:14ZengElsevierRadiology Case Reports1930-04332020-10-01151018641869Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patientDimitri A. Parra, MD0Leonardo Brandao, MD1Division of Image Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, Room 2230A, 555 University Ave, Toronto, ON M5G 1X8, Canada; Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Corresponding author.Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, CanadaDrug-coated balloons (DCB) are a treatment alternative to conventional angioplasty in arterial, hemodialysis fistulas, and venous stenoses. This case report describes a child with the diagnosis of hepatoblastoma treated with chemotherapy and a right extended hepatectomy with venous reconstruction. The patient presented with signs and symptoms of portal hypertension due to a hepatic venous outflow obstruction secondary to stenosis of the surgical anastomosis. The response to conventional angioplasty was limited with frequent recurrence of symptoms. DCBs were used as an alternative prior to stent consideration aiming to assess if these devices could provide improvement of the symptoms and as a long-term therapy. The use of DCBs increased the time interval of reinterventions in comparison with conventional angioplasty. The patient eventually required stents due to recurrence of the primary disease.While this report does not provide an in-depth evaluation in terms of the efficacy and safety of DCB, this case illustrates a potential novel treatment modality to be considered for children, when stenotic venous lesions not amenable for stenting are present.http://www.sciencedirect.com/science/article/pii/S1930043320303551Hepatic vein stenosisDrug coated balloonAngioplasty |
| spellingShingle | Dimitri A. Parra, MD Leonardo Brandao, MD Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient Radiology Case Reports Hepatic vein stenosis Drug coated balloon Angioplasty |
| title | Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| title_full | Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| title_fullStr | Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| title_full_unstemmed | Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| title_short | Use of drug-coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| title_sort | use of drug coated balloons in the management of a recalcitrant postsurgical hepatic vein stenosis in a pediatric patient |
| topic | Hepatic vein stenosis Drug coated balloon Angioplasty |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320303551 |
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