COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru
During the COVID-19 pandemic, a new, severe and unusual condition called Multisystem Inflammatory Syndrome in children emerged, from which there is still much to learn. We report 8 children admitted to Instituto Nacional de Salud del Niño, in Lima, Perú. Their mean age was 5,1 years. Their clinical...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | Spanish |
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Instituto Nacional de Salud
2020-09-01
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| Series: | Revista Peruana de Medicina Experimental y Salud Pública |
| Subjects: | |
| Online Access: | https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6126 |
| _version_ | 1818159001026691072 |
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| author | Liz E. De Coll-Vela Mariela K. Zamudio-Aquise Héctor Nuñez-Paucar Raúl R. Bernal-Mancilla Sandra C. Schult-Montoya Manuel Ccorahua-De La Paz Cynthia L. Huby-Muñoz Carlos F. Castillo-Torres Jorge L. Candela-Herrera Franklin Aranda-Paniora Raúl A. Rojas-Galarza |
| author_facet | Liz E. De Coll-Vela Mariela K. Zamudio-Aquise Héctor Nuñez-Paucar Raúl R. Bernal-Mancilla Sandra C. Schult-Montoya Manuel Ccorahua-De La Paz Cynthia L. Huby-Muñoz Carlos F. Castillo-Torres Jorge L. Candela-Herrera Franklin Aranda-Paniora Raúl A. Rojas-Galarza |
| author_sort | Liz E. De Coll-Vela |
| collection | DOAJ |
| description | During the COVID-19 pandemic, a new, severe and unusual condition called Multisystem Inflammatory Syndrome in children emerged, from which there is still much to learn. We report 8 children admitted to Instituto Nacional de Salud del Niño, in Lima, Perú. Their mean age was 5,1 years. Their clinical presentation included fever, acute gastrointestinal symptoms, ocular and mucocutaneous involvement. Four patients met criteria for classic Kawasaki Disease. All the patients had positive serology for SARS-CoV-2, abnormal complete blood counts and coagulation tests, and elevated inflammatory markers. Five had elevated liver enzymes and three had kidney involvement. Four patients met criteria for Macrophage Activation Syndrome. All of them received intravenous immune globulin, corticosteroids and aspirin. No coronary aneurysms were identified. Only one developed miocarditis, shock and was admitted to the Pediatric Intensive Care Unit. Most patients recovered successfully. Every child with fever, gastrointestinal and dermatological symptoms, associated with prior exposure to SARS-CoV-2, should be investigated for multi-systemic compromise. |
| first_indexed | 2024-12-11T15:39:02Z |
| format | Article |
| id | doaj.art-6d1f967e22a74319bde53dae907a5f95 |
| institution | Directory Open Access Journal |
| issn | 1726-4634 1726-4642 |
| language | Spanish |
| last_indexed | 2024-12-11T15:39:02Z |
| publishDate | 2020-09-01 |
| publisher | Instituto Nacional de Salud |
| record_format | Article |
| series | Revista Peruana de Medicina Experimental y Salud Pública |
| spelling | doaj.art-6d1f967e22a74319bde53dae907a5f952022-12-22T00:59:52ZspaInstituto Nacional de SaludRevista Peruana de Medicina Experimental y Salud Pública1726-46341726-46422020-09-013735596510.17843/rpmesp.2020.373.61262388COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in PeruLiz E. De Coll-Vela0Mariela K. Zamudio-Aquise1Héctor Nuñez-Paucar2Raúl R. Bernal-Mancilla3Sandra C. Schult-Montoya4Manuel Ccorahua-De La Paz5Cynthia L. Huby-Muñoz6Carlos F. Castillo-Torres7Jorge L. Candela-Herrera8Franklin Aranda-Paniora9Raúl A. Rojas-Galarza10Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Peruana Cayetano Heredia, Lima, Perú. Médico Pediatra NeumólogoInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra NeumólogoInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Médico Pediatra NeumólogoInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad de San Martín de Porres, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad de San Martín de Porres, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Peruana Cayetano Heredia, Lima, Perú. Médico Pediatra InfectólogoInstituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico PediatraInstituto Nacional de Salud del Niño Breña, Lima, Perú. Médico Pediatra Gastroenterólogo.During the COVID-19 pandemic, a new, severe and unusual condition called Multisystem Inflammatory Syndrome in children emerged, from which there is still much to learn. We report 8 children admitted to Instituto Nacional de Salud del Niño, in Lima, Perú. Their mean age was 5,1 years. Their clinical presentation included fever, acute gastrointestinal symptoms, ocular and mucocutaneous involvement. Four patients met criteria for classic Kawasaki Disease. All the patients had positive serology for SARS-CoV-2, abnormal complete blood counts and coagulation tests, and elevated inflammatory markers. Five had elevated liver enzymes and three had kidney involvement. Four patients met criteria for Macrophage Activation Syndrome. All of them received intravenous immune globulin, corticosteroids and aspirin. No coronary aneurysms were identified. Only one developed miocarditis, shock and was admitted to the Pediatric Intensive Care Unit. Most patients recovered successfully. Every child with fever, gastrointestinal and dermatological symptoms, associated with prior exposure to SARS-CoV-2, should be investigated for multi-systemic compromise.https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6126enfermedad por coronavirus 2019-ncovenfermedad de kawasakiniñoinmunoglobulinas intravenosas |
| spellingShingle | Liz E. De Coll-Vela Mariela K. Zamudio-Aquise Héctor Nuñez-Paucar Raúl R. Bernal-Mancilla Sandra C. Schult-Montoya Manuel Ccorahua-De La Paz Cynthia L. Huby-Muñoz Carlos F. Castillo-Torres Jorge L. Candela-Herrera Franklin Aranda-Paniora Raúl A. Rojas-Galarza COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru Revista Peruana de Medicina Experimental y Salud Pública enfermedad por coronavirus 2019-ncov enfermedad de kawasaki niño inmunoglobulinas intravenosas |
| title | COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru |
| title_full | COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru |
| title_fullStr | COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru |
| title_full_unstemmed | COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru |
| title_short | COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru |
| title_sort | covid 19 associated multisystem inflammatory syndrome in children case series at a pediatric hospital in peru |
| topic | enfermedad por coronavirus 2019-ncov enfermedad de kawasaki niño inmunoglobulinas intravenosas |
| url | https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6126 |
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