Assessment of global histone acetylation in pediatric and adolescent obesity: Correlations with SIRT1 expression and metabolic-inflammatory profiles.

<h4>Background</h4>Epigenetic modifications, particularly histone acetylation-deacetylation and its related enzymes, such as sirtuin 1 (SIRT1) deacetylase, may have substantial roles in the pathogenesis of obesity and its associated health issues. This study aimed to evaluate global hist...

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Main Authors: Nima Taghizadeh, Soha Mohammadi, Zeynab Yousefi, Pegah Golpour, Alemeh Taheri, Mohammad Hasan Maleki, Mitra Nourbakhsh, Mona Nourbakhsh, Maryam Razzaghy Azar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0293217