Natural killer cell based therapies targeting cancer: Possible strategies to gain and sustain anti-tumor activity

Natural killer cell based therapies targeting cancer: Possible strategies to gain and sustain anti-tumor activity

Natural killer (NK) cells were discovered 40 years ago, by their ability to recognize and kill tumor cells without the requirement of prior antigen exposure. Since then NK cells have been seen as promising agents for cell-based cancer therapies. However, NK cells represent only a minor fraction of t...

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Bibliographic Details
Main Authors: Carin I.M. Dahlberg, Dhifaf eSarhan, Michael eChrobok, Adil Doganay Duru, Evren eAlici
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Immunology
Subjects:
Immunotherapy
Tumor Microenvironment
Cancer
clinical trials
monoclonal antibodies
Natural Killer cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00605/full

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