A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells
In recent years, sphingolipids have attracted significant attention due to their pivotal role in cellular functions and physiological diseases. A valuable tool for investigating the characteristics of sphingolipids can be represented via FT-IR spectroscopy, generally recognized as a very powerful te...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Biophysica |
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| Online Access: | https://www.mdpi.com/2673-4125/3/1/11 |
| _version_ | 1827751017270214656 |
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| author | Bahar Faramarzi Martina Moggio Nadia Diano Marianna Portaccio Maria Lepore |
| author_facet | Bahar Faramarzi Martina Moggio Nadia Diano Marianna Portaccio Maria Lepore |
| author_sort | Bahar Faramarzi |
| collection | DOAJ |
| description | In recent years, sphingolipids have attracted significant attention due to their pivotal role in cellular functions and physiological diseases. A valuable tool for investigating the characteristics of sphingolipids can be represented via FT-IR spectroscopy, generally recognized as a very powerful technique that provides detailed biochemical information on the examined sample with the unique properties of sensitivity and accuracy. In the present paper, some fundamental aspects of sphingolipid components of human cells are summarized, and the most relevant articles devoted to the FT-IR spectroscopic studies of sphingolipids are revised. A short description of different FT-IR experimental approaches adopted for investigating sphingolipids is also given, with details about the most commonly used data analysis procedures. The present overview of FT-IR investigations, although not exhaustive, attests to the relevant role this vibrational technique has played in giving significant insight into many aspects of this fascinating class of lipids. |
| first_indexed | 2024-03-11T06:52:34Z |
| format | Article |
| id | doaj.art-6d2bdd0d06354eceb2f40f9d762a4d59 |
| institution | Directory Open Access Journal |
| issn | 2673-4125 |
| language | English |
| last_indexed | 2024-03-11T06:52:34Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biophysica |
| spelling | doaj.art-6d2bdd0d06354eceb2f40f9d762a4d592023-11-17T09:53:22ZengMDPI AGBiophysica2673-41252023-03-013115818010.3390/biophysica3010011A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human CellsBahar Faramarzi0Martina Moggio1Nadia Diano2Marianna Portaccio3Maria Lepore4Dipartimento di Matematica e Fisica, Università della Campania “Luigi Vanvitelli”, 81100 Caserta, ItalyDipartimento di Medicina Sperimentale, Università della Campania “Luigi Vanvitelli”, 80138 Napoli, ItalyDipartimento di Medicina Sperimentale, Università della Campania “Luigi Vanvitelli”, 80138 Napoli, ItalyDipartimento di Medicina Sperimentale, Università della Campania “Luigi Vanvitelli”, 80138 Napoli, ItalyDipartimento di Medicina Sperimentale, Università della Campania “Luigi Vanvitelli”, 80138 Napoli, ItalyIn recent years, sphingolipids have attracted significant attention due to their pivotal role in cellular functions and physiological diseases. A valuable tool for investigating the characteristics of sphingolipids can be represented via FT-IR spectroscopy, generally recognized as a very powerful technique that provides detailed biochemical information on the examined sample with the unique properties of sensitivity and accuracy. In the present paper, some fundamental aspects of sphingolipid components of human cells are summarized, and the most relevant articles devoted to the FT-IR spectroscopic studies of sphingolipids are revised. A short description of different FT-IR experimental approaches adopted for investigating sphingolipids is also given, with details about the most commonly used data analysis procedures. The present overview of FT-IR investigations, although not exhaustive, attests to the relevant role this vibrational technique has played in giving significant insight into many aspects of this fascinating class of lipids.https://www.mdpi.com/2673-4125/3/1/11sphingolipidssphingomyelinsphingosineceramidehuman cellsFT-IR spectroscopy |
| spellingShingle | Bahar Faramarzi Martina Moggio Nadia Diano Marianna Portaccio Maria Lepore A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells Biophysica sphingolipids sphingomyelin sphingosine ceramide human cells FT-IR spectroscopy |
| title | A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells |
| title_full | A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells |
| title_fullStr | A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells |
| title_full_unstemmed | A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells |
| title_short | A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells |
| title_sort | brief review of ft ir spectroscopy studies of sphingolipids in human cells |
| topic | sphingolipids sphingomyelin sphingosine ceramide human cells FT-IR spectroscopy |
| url | https://www.mdpi.com/2673-4125/3/1/11 |
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