MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure

The present 1D photonic biosensor is composed of two sub-PhCs of alternate layers made of GaP and SiO<sub>2</sub>. The period number of each PhC has been fixed to 3. Both these PhCs are joined together through a cavity region of air in which different analytes are to be filled one by one...

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Main Authors: Arafa H. Aly, S. K. Awasthi, M. A. Mohaseb, Z. S. Matar, A. F. Amin
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/12/2/220
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author Arafa H. Aly
S. K. Awasthi
M. A. Mohaseb
Z. S. Matar
A. F. Amin
author_facet Arafa H. Aly
S. K. Awasthi
M. A. Mohaseb
Z. S. Matar
A. F. Amin
author_sort Arafa H. Aly
collection DOAJ
description The present 1D photonic biosensor is composed of two sub-PhCs of alternate layers made of GaP and SiO<sub>2</sub>. The period number of each PhC has been fixed to 3. Both these PhCs are joined together through a cavity region of air in which different analytes are to be filled one by one under the scope of this study. The theoretical findings of this work have been formulated with the help of the well-known transfer matrix method. Moreover, all the computations pertaining to this work have been carried out with the help of MATLAB software. The effect of change in cavity thickness and angle of incidence corresponding to a TE wave on the transmittance of the structure (AB)ND(AB)N has been studied theoretically which in turn determines the performance of the proposed biosensor. Various parameters, such as sensitivity (S), signal to noise ratio (SNR), figure of merit (FOM), resolution (RS), detection limit (LOD), quality factor (Q) and dynamic range (DR) have been theoretically calculated to evaluate the performance of the proposed design in true sense. The sensitivity of this structure varies between the highest and lowest values of 337.3626 nm/RIU and 333.0882 nm/RIU corresponding to water samples containing <i>Pseudomonas aeruginosa cells</i> and <i>Bacillus anthracia cells</i>, respectively, under normal incidence condition with a cavity thickness of 2.0 µm. The resolution (in nm) and LOD (in RIU) values of the proposed design are small enough and are significant for our structure. This study may also be helpful for distinguishing various microbiological samples under investigation and find suitable applications for discriminating bacterial cells from spores.
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spelling doaj.art-6d2c20b0266748539881c9ebbff5017d2023-11-23T19:24:52ZengMDPI AGCrystals2073-43522022-02-0112222010.3390/cryst12020220MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic StructureArafa H. Aly0S. K. Awasthi1M. A. Mohaseb2Z. S. Matar3A. F. Amin4TH-PPM Group, Physics Department, Faculty of Sciences, Beni-Suef University, Beni Suef 62111, EgyptDepartment of Physics and Material Science and Engineering, Jaypee Institute of Information Technology, Noida 201304, IndiaTH-PPM Group, Physics Department, Faculty of Sciences, Beni-Suef University, Beni Suef 62111, EgyptDepartment of Physics, Faculty of Applied Science, Umm Al-Qura University, Mecca 24381, Saudi ArabiaFaculty of Technology and Education, Beni-Suef University, Beni Suef 62111, EgyptThe present 1D photonic biosensor is composed of two sub-PhCs of alternate layers made of GaP and SiO<sub>2</sub>. The period number of each PhC has been fixed to 3. Both these PhCs are joined together through a cavity region of air in which different analytes are to be filled one by one under the scope of this study. The theoretical findings of this work have been formulated with the help of the well-known transfer matrix method. Moreover, all the computations pertaining to this work have been carried out with the help of MATLAB software. The effect of change in cavity thickness and angle of incidence corresponding to a TE wave on the transmittance of the structure (AB)ND(AB)N has been studied theoretically which in turn determines the performance of the proposed biosensor. Various parameters, such as sensitivity (S), signal to noise ratio (SNR), figure of merit (FOM), resolution (RS), detection limit (LOD), quality factor (Q) and dynamic range (DR) have been theoretically calculated to evaluate the performance of the proposed design in true sense. The sensitivity of this structure varies between the highest and lowest values of 337.3626 nm/RIU and 333.0882 nm/RIU corresponding to water samples containing <i>Pseudomonas aeruginosa cells</i> and <i>Bacillus anthracia cells</i>, respectively, under normal incidence condition with a cavity thickness of 2.0 µm. The resolution (in nm) and LOD (in RIU) values of the proposed design are small enough and are significant for our structure. This study may also be helpful for distinguishing various microbiological samples under investigation and find suitable applications for discriminating bacterial cells from spores.https://www.mdpi.com/2073-4352/12/2/220bacterial cellsphotonic crystalsbiosensingdetecting bacterial cellssensitivity
spellingShingle Arafa H. Aly
S. K. Awasthi
M. A. Mohaseb
Z. S. Matar
A. F. Amin
MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
Crystals
bacterial cells
photonic crystals
biosensing
detecting bacterial cells
sensitivity
title MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
title_full MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
title_fullStr MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
title_full_unstemmed MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
title_short MATLAB Simulation-Based Theoretical Study for Detection of a Wide Range of Pathogens Using 1D Defective Photonic Structure
title_sort matlab simulation based theoretical study for detection of a wide range of pathogens using 1d defective photonic structure
topic bacterial cells
photonic crystals
biosensing
detecting bacterial cells
sensitivity
url https://www.mdpi.com/2073-4352/12/2/220
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